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MedKoo Cat#: 563496 | Name: EIPA
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

EIPA is a selective blocker of Na+/H+ antiport.

Chemical Structure

EIPA
EIPA
CAS#1154-25-2 (free base)

Theoretical Analysis

MedKoo Cat#: 563496

Name: EIPA

CAS#: 1154-25-2 (free base)

Chemical Formula: C11H18ClN7O

Exact Mass: 299.1261

Molecular Weight: 299.76

Elemental Analysis: C, 44.08; H, 6.05; Cl, 11.83; N, 32.71; O, 5.34

Price and Availability

Size Price Availability Quantity
10mg USD 350.00 2 Weeks
25mg USD 650.00 2 Weeks
50mg USD 950.00 2 Weeks
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Related CAS #
1154-25-2 (free base) 1345839-28-2 (HCl)
Synonym
EIPA; Ethylisopropylamiloride; 5-(Ethylisopropyl)amiloride; L-593,754; L 593,754; L593,754; MH 12-43; MH-12-43; MH12-43;
IUPAC/Chemical Name
3-Amino-6-chloro-N-(diaminomethylidene)-5-[ethyl(propan-2-yl)amino]pyrazine-2-carboxamide
InChi Key
QDERNBXNXJCIQK-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H18ClN7O/c1-4-19(5(2)3)9-7(12)16-6(8(13)17-9)10(20)18-11(14)15/h5H,4H2,1-3H3,(H2,13,17)(H4,14,15,18,20)
SMILES Code
3-Amino-6-chloro-N-(diaminomethylidene)-5-[ethyl(propan-2-yl)amino]pyrazine-2-carboxamide
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 299.76 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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J Comp Physiol B. 2017 Oct;187(7):1019-1028. doi: 10.1007/s00360-017-1063-z. Epub 2017 Feb 28. PubMed PMID: 28247055. 11: Wang D, Zhou Y, Li X, Qu X, Deng Y, Wang Z, He C, Zou Y, Jin Y, Liu Y. Mechanisms of pH-Sensitivity and Cellular Internalization of PEOz-b-PLA Micelles with Varied Hydrophilic/Hydrophobic Ratios and Intracellular Trafficking Routes and Fate of the Copolymer. ACS Appl Mater Interfaces. 2017 Mar 1;9(8):6916-6930. doi: 10.1021/acsami.6b16376. Epub 2017 Feb 17. PubMed PMID: 28186394. 12: Studer N, Gundelfinger R, Schenker T, Steinhausen HC. Implementation of early intensive behavioural intervention for children with autism in Switzerland. BMC Psychiatry. 2017 Jan 21;17(1):34. doi: 10.1186/s12888-017-1195-4. PubMed PMID: 28109262; PubMed Central PMCID: PMC5251245. 13: Zhu BY, Shang BY, Du Y, Li Y, Li L, Xu XD, Zhen YS. A new HDAC inhibitor cinnamoylphenazine shows antitumor activity in association with intensive macropinocytosis. 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