MedKoo Cat#: 130340 | Name: PTAD-Azide
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

PTAD-Azide is a crosslinking reagent used in the formation of hydrogels, for protein modifications, and in e-Y-CLICK chemistry. PTAD-Azide has the ability to introduce PEG chains onto proteins that have exposed tyrosine residues on the surface.

Chemical Structure

PTAD-Azide
PTAD-Azide
CAS# 1313211-52-7

Theoretical Analysis

MedKoo Cat#: 130340

Name: PTAD-Azide

CAS#: 1313211-52-7

Chemical Formula: C10H10N6O3

Exact Mass: 262.0814

Molecular Weight: 262.23

Elemental Analysis: C, 45.80; H, 3.84; N, 32.05; O, 18.30

Price and Availability

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50mg USD 575.00 2 Weeks
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Related CAS #
No Data
Synonym
PTAD-Azide; PTAD Azide;
IUPAC/Chemical Name
4-(4-(2-azidoethoxy)phenyl)-1,2,4-triazolidine-3,5-dione
InChi Key
MHGMHPVYCVQIET-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H10N6O3/c11-15-12-5-6-19-8-3-1-7(2-4-8)16-9(17)13-14-10(16)18/h1-4H,5-6H2,(H,13,17)(H,14,18)
SMILES Code
O=C(N1C2=CC=C(OCCN=[N+]=[N-])C=C2)NNC1=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 262.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Madl CM, Heilshorn SC. Tyrosine-Selective Functionalization for Bio-Orthogonal Cross-Linking of Engineered Protein Hydrogels. Bioconjug Chem. 2017 Mar 15;28(3):724-730. doi: 10.1021/acs.bioconjchem.6b00720. Epub 2017 Feb 2. PMID: 28151642; PMCID: PMC7274545. 2. Moinpour M, Barker NK, Guzman LE, Jewett JC, Langlais PR, Schwartz JC. Discriminating changes in protein structure using tyrosine conjugation. Protein Sci. 2020 Aug;29(8):1784-1793. doi: 10.1002/pro.3897. Epub 2020 Jul 6. PMID: 32483864; PMCID: PMC7380675.