Kijimicin Na | CAS# 129388-64-3 (Na) | polyether antibiotic

MedKoo Cat#: 414243 | Name: Kijimicin Na

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Kijimicin Na is the salt form of Kijimicin Free Base, a polyether antibiotic and inhibitor of human immunodeficiency virus in acutely and chronically infected cells.

Chemical Structure

Kijimicin Na

CAS# 129388-64-3 (Na)

Theoretical Analysis

MedKoo Cat#: 414243

Name: Kijimicin Na

CAS#: 129388-64-3 (Na)

Chemical Formula: C36H61NaO11

Exact Mass:

Molecular Weight: 692.86

Elemental Analysis: C, 62.41; H, 8.87; Na, 3.32; O, 25.40

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

129297-22-9 (free base) 129388-64-3 (Na)

Synonym

Kijimicin Na; Kijimicin sodium

IUPAC/Chemical Name

sodium 4-(2-(2''-hydroxy-5''-(1-hydroxyethyl)-2,3',3'',5''-tetramethyldodecahydro-[2,2':5',2''-terfuran]-5-yl)-9-methoxy-8,10-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl)-3-methoxy-2-methylpentanoate

InChi Key

UDOHHZKVYJCKFR-UHFFFAOYSA-M

InChi Code

InChI=1S/C36H62O11.Na/c1-18-16-27(36(40)19(2)17-34(9,47-36)24(7)37)43-31(18)33(8)14-12-25(44-33)26-13-15-35(45-26)23(6)30(42-11)21(4)29(46-35)20(3)28(41-10)22(5)32(38)39;/h18-31,37,40H,12-17H2,1-11H3,(H,38,39);/q;+1/p-1

SMILES Code

COC(C(C([O-])=O)C)C(C1OC2(C(C(C1C)OC)C)CCC(C3CCC(O3)(C4OC(C5(OC(CC5C)(C(O)C)C)O)CC4C)C)O2)C.[Na+]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 692.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Yamauchi T, Nakamura M, Honma H, Ikeda M, Kawashima K, Ohno T. Mechanistic effects of kijimicin on inhibition of human immunodeficiency virus replication. Mol Cell Biochem. 1993 Feb 17;119(1-2):35-41. PubMed PMID: 8455584. 2: Takahashi Y, Nakamura H, Ogata R, Matsuda N, Hamada M, Naganawa H, Takita T, Iitaka Y, Sato K, Takeuchi T. Kijimicin, a polyether antibiotic. J Antibiot (Tokyo). 1990 Apr;43(4):441-3. PubMed PMID: 2351616. 3: Nakamura M, Ohno T, Kunimoto S, Naganawa H, Takeuchi T. Kijimicin: an inhibitor of human immunodeficiency virus in acutely and chronically infected cells. J Antibiot (Tokyo). 1991 May;44(5):569-71. PubMed PMID: 2061199.