Kijimicin | CAS# 129297-22-9 (free base)| antibiotic

MedKoo Cat#: 558518 | Name: Kijimicin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Kijimicin is a polyether antibiotic and inhibitor of human immunodeficiency virus in acutely and chronically infected cells.

Chemical Structure

Kijimicin

CAS#129297-22-9 (free base)

Theoretical Analysis

MedKoo Cat#: 558518

Name: Kijimicin

CAS#: 129297-22-9 (free base)

Chemical Formula: C37H64O11

Exact Mass: 684.4400

Molecular Weight: 684.91

Elemental Analysis: C, 64.89; H, 9.42; O, 25.70

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

129297-22-9 (free base) 129388-64-3 (Na)

Synonym

Kijimicin; Kijimycin;

IUPAC/Chemical Name

4-(2-(2''-hydroxy-5''-(1-hydroxypropyl)-2,3',3'',5''-tetramethyldodecahydro-[2,2':5',2''-terfuran]-5-yl)-9-methoxy-8,10-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl)-3-methoxy-2-methylpentanoic acid

InChi Key

DQQFPJYHEYSNAS-UHFFFAOYSA-N

InChi Code

InChI=1S/C37H64O11/c1-12-27(38)35(9)18-20(3)37(41,48-35)28-17-19(2)32(44-28)34(8)15-13-25(45-34)26-14-16-36(46-26)24(7)31(43-11)22(5)30(47-36)21(4)29(42-10)23(6)33(39)40/h19-32,38,41H,12-18H2,1-11H3,(H,39,40)

SMILES Code

CC(C(C(C)C(OC)C1C)OC21CCC(C3CCC(C4OC(C5(O)OC(C)(C(O)CC)CC5C)CC4C)(C)O3)O2)C(OC)C(C)C(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 684.91 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Yamauchi T, Nakamura M, Honma H, Ikeda M, Kawashima K, Ohno T. Mechanistic effects of kijimicin on inhibition of human immunodeficiency virus replication. Mol Cell Biochem. 1993 Feb 17;119(1-2):35-41. PubMed PMID: 8455584. 2: Takahashi Y, Nakamura H, Ogata R, Matsuda N, Hamada M, Naganawa H, Takita T, Iitaka Y, Sato K, Takeuchi T. Kijimicin, a polyether antibiotic. J Antibiot (Tokyo). 1990 Apr;43(4):441-3. PubMed PMID: 2351616. 3: Nakamura M, Ohno T, Kunimoto S, Naganawa H, Takeuchi T. Kijimicin: an inhibitor of human immunodeficiency virus in acutely and chronically infected cells. J Antibiot (Tokyo). 1991 May;44(5):569-71. PubMed PMID: 2061199.