IUPAC/Chemical Name
3,10-dibenzyl-1,8-dioxa-3,10-diazadispiro[3.2.37.24]dodeca-5,11-diene-2,9-dithione
InChi Key
OGWNPNIRZURLGD-UHFFFAOYSA-N
InChi Code
1S/C22H18N2O2S2/c27-19-23(15-17-7-3-1-4-8-17)21(25-19)11-13-22(14-12-21)24(20(28)26-22)16-18-9-5-2-6-10-18/h1-14H,15-16H2
SMILES Code
S=C1OC2(C=CC3(OC(=S)N3CC4=CC=CC=C4)C=C2)N1CC5=CC=CC=C5
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
406.52
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: RAO RR, GEORGE M, PANDALAI KM. Pterygospermin; the antibacterial principle of Moringa pterygosperma, Gaertn. Nature. 1946 Nov 23;158(4021):745. doi: 10.1038/158745b0. PMID: 20341204.
2: Enmozhi SK, Xavier I, Raaj T, Sarveswaran R, Blessings J, Kesavamoorthy Y, Vivek R, Raja K, Sebastine I, Jeffri A, Arockiasamy S, Joseph J, Rani A. Recuperative potential of Indian medicinal plant compounds- a tool to encumber henipaviruses: an in -silico study. In Silico Pharmacol. 2024 Aug 2;12(2):72. doi: 10.1007/s40203-024-00236-x. PMID: 39099797; PMCID: PMC11294312.
3: DAS BR, KURUP PA, NARASIMHA RAO PL. Antibiotic principle from Moringa pterygosperma. VII. Antibacterial activity and chemical structure of compounds related to pterygospermin. Indian J Med Res. 1957 Apr;45(2):191-6. PMID: 13438557.
4: KURUP PA, RAO PL, VENKATARAMAN R. Antibiotic principle from Moringa pterygosperma. VI. Mechanism of antibacterial action of pterygospermin inhibition of transaminase by pterygospermin. Indian J Med Res. 1954 Jan;42(1):115-23. PMID: 13162513.
5: KURUP PA, RAO PL. Antibiotic principle from Moringa pterygosperma. IV. The effect of addition of vitamins and amino acids on the anti-bacterial activity of pterygospermin. Indian J Med Res. 1954 Jan;42(1):101-7. PMID: 13162511.
6: KURUP PA, RAO PL. Antibiotic principle from Moringa pterygosperma. V. Effect of pterygospermin on the assimilation of glutamic acid by Micrococcus pyogenes var. aureus. Indian J Med Res. 1954 Jan;42(1):109-14. PMID: 13162512.
7: KURUP PA, RAO PL. Antibiotic principle from Moringa pterygosperma. II. Chemical nature of pterygospermin. Indian J Med Res. 1954 Jan;42(1):85-95. PMID: 13162509.
8: GOPALAKRISHNA KS, KURUP PA, RAO PL. Antibiotic principles from Moringa pterygosperma. III. Action of pterygospermin on germination of seeds and filamentous fungi. Indian J Med Res. 1954 Jan;42(1):97-9. PMID: 13162510.
9: DAS BR, KURUP PA, NARASIMHA RAO PL, RAMASWAMY AS. Antibiotic principle from Moringa pterygosperma. VIII. Some pharmacological properties and in vivo action of pterygospermin and related compounds. Indian J Med Res. 1957 Apr;45(2):197-206. PMID: 13438558.
