LY 81067 | CAS#87186-60-5 | anticonvulsive agent

MedKoo Cat#: 598882 | Name: LY 81067

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LY 81067 is a new anticonvulsive agent.

Chemical Structure

LY 81067

CAS#87186-60-5

Theoretical Analysis

MedKoo Cat#: 598882

Name: LY 81067

CAS#: 87186-60-5

Chemical Formula: C22H24N4O

Exact Mass: 360.1950

Molecular Weight: 360.46

Elemental Analysis: C, 73.31; H, 6.71; N, 15.54; O, 4.44

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

LY 81067; LY-81067; LY81067; Lilly 81067; Lilly-81067; Lilly81067;

IUPAC/Chemical Name

1-(5,6-di-p-tolyl-1,2,4-triazin-3-yl)piperidin-4-ol

InChi Key

DIASUTCRTFLJTA-UHFFFAOYSA-N

InChi Code

InChI=1S/C22H24N4O/c1-15-3-7-17(8-4-15)20-21(18-9-5-16(2)6-10-18)24-25-22(23-20)26-13-11-19(27)12-14-26/h3-10,19,27H,11-14H2,1-2H3

SMILES Code

OC1CCN(C2=NC(C3=CC=C(C)C=C3)=C(C4=CC=C(C)C=C4)N=N2)CC1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 360.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Wong DT, Threlkeld PG, Bymaster FP, Squires RF. Saturable binding of 35S-t-butylbicyclophosphorothionate to the sites linked to the GABA receptor and the interaction with GABAergic agents. Life Sci. 1984 Feb 27;34(9):853-60. PubMed PMID: 6321873. 2: Wong DT, Rathbun RC, Bymaster FP, Lacefield WB. Enhanced binding of radioligands to receptors of gamma-aminobutyric acid and benzodiazepine by a new anticonvulsive agent, LY81067. Life Sci. 1983 Sep 5;33(10):917-23. PubMed PMID: 6310287. 3: Brouillet E, Chavoix C, de la Sayette V, Hantraye P, Kunimoto M, Khalili-Varasteh M, Guibert B, Fournier D, Dodd RH, Naquet R, et al. Anticonvulsant activity of the diaryltriazine, LY81067: studies using electroencephalographic recording and positron emission tomography. Neuropharmacology. 1989 Apr;28(4):351-8. PubMed PMID: 2501707.