MedKoo Cat#: 462521 | Name: EIPA hydrochloride
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

EIPA hydrochloride is a TRPP3 channel inhibitor.

Chemical Structure

EIPA hydrochloride
EIPA hydrochloride
CAS#1345839-28-2 (HCl)

Theoretical Analysis

MedKoo Cat#: 462521

Name: EIPA hydrochloride

CAS#: 1345839-28-2 (HCl)

Chemical Formula: C11H19Cl2N7O

Exact Mass: 335.1028

Molecular Weight: 336.22

Elemental Analysis: C, 39.30; H, 5.70; Cl, 21.09; N, 29.16; O, 4.76

Price and Availability

Size Price Availability Quantity
5mg USD 265.00 2 Weeks
10mg USD 450.00 2 Weeks
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Synonym
EIPA hydrochloride; EIPA (hydrochloride); L593754 hydrochloride; L 593754 hydrochloride; L-593754 hydrochloride; L-593754 HCl
IUPAC/Chemical Name
3-amino-N-carbamimidoyl-6-chloro-5-(ethyl(isopropyl)amino)pyrazine-2-carboxamide hydrochloride
InChi Key
BGHBOQNLQNKPFO-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H18ClN7O.ClH/c1-4-19(5(2)3)9-7(12)16-6(8(13)17-9)10(20)18-11(14)15;/h5H,4H2,1-3H3,(H2,13,17)(H4,14,15,18,20);1H
SMILES Code
O=C(C1=NC(Cl)=C(N(CC)C(C)C)N=C1N)NC(N)=N.Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 336.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Dai XQ, Ramji A, Liu Y, Li Q, Karpinski E, Chen XZ. Inhibition of TRPP3 channel by amiloride and analogs. Mol Pharmacol. 2007;72(6):1576-1585. doi:10.1124/mol.107.037150 2: Shi H, Zhao X, Ding Z, et al. Na+/H+ Exchanger Regulates Amino Acid-Mediated Autophagy in Intestinal Epithelial Cells. Cell Physiol Biochem. 2017;42(6):2418-2429. doi:10.1159/000480184 3: Zhu BY, Shang BY, Du Y, et al. A new HDAC inhibitor cinnamoylphenazine shows antitumor activity in association with intensive macropinocytosis. Oncotarget. 2017;8(9):14748-14758. doi:10.18632/oncotarget.14714