MedKoo Cat#: 127771 | Name: KISS1-305 (trifluoroacetate salt)
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

KISS1 305 is a potent Kisspeptin1 receptor agonist.

Chemical Structure

KISS1-305 (trifluoroacetate salt)
KISS1-305 (trifluoroacetate salt)
CAS#KISS1-305 (trifluoroacetate salt)

Theoretical Analysis

MedKoo Cat#: 127771

Name: KISS1-305 (trifluoroacetate salt)

CAS#: KISS1-305 (trifluoroacetate salt)

Chemical Formula: C58H77F3N16O14

Exact Mass: 1278.5757

Molecular Weight: 1279.35

Elemental Analysis: C, 54.45; H, 6.07; F, 4.46; N, 17.52; O, 17.51

Price and Availability

Size Price Availability Quantity
1mg USD 550.00 2 Weeks
5mg USD 1,250.00 2 Weeks
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Synonym
KISS1-305 (trifluoroacetate salt); KISS1-305 trifluoroacetate salt; KISS1-305; KISS1305; KISS1 305
IUPAC/Chemical Name
(S)-N1-((8S,11S,17S,20S)-8-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)carbamoyl)-17-benzyl-21-hydroxy-3-imino-11-isobutyl-10,13,16,19-tetraoxo-2,4,9,12,14,15,18-heptaazahenicosan-20-yl)-2-((R)-2-((R)-2-amino-3-(4-hydroxyphenyl)propanamido)-3-(pyridin-4-yl)propanamido)succinamide 2,2,2-trifluoroacetate
InChi Key
IWIAGCCSJHRYHC-ITKFFJNWSA-N
InChi Code
InChI=1S/C56H76N16O12.C2HF3O2/c1-32(2)25-41(50(79)64-39(15-10-22-63-55(60)61-3)49(78)65-40(47(59)76)27-33-11-6-4-7-12-33)70-56(84)72-71-54(83)43(28-34-13-8-5-9-14-34)67-53(82)45(31-73)69-52(81)44(30-46(58)75)68-51(80)42(29-36-20-23-62-24-21-36)66-48(77)38(57)26-35-16-18-37(74)19-17-35;3-2(4,5)1(6)7/h4-9,11-14,16-21,23-24,32,38-45,73-74H,10,15,22,25-31,57H2,1-3H3,(H2,58,75)(H2,59,76)(H,64,79)(H,65,78)(H,66,77)(H,67,82)(H,68,80)(H,69,81)(H,71,83)(H3,60,61,63)(H2,70,72,84);(H,6,7)/t38-,39+,40+,41+,42-,43+,44+,45+;/m1./s1
SMILES Code
NC([C@H](CC1=CC=CC=C1)NC([C@H](CCCNC(NC)=N)NC([C@H](CC(C)C)NC(NNC([C@H](CC2=CC=CC=C2)NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@H](NC([C@H](N)CC3=CC=C(C=C3)O)=O)CC4=CC=NC=C4)=O)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,279.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Matsui H, Tanaka A, Yokoyama K, Takatsu Y, Ishikawa K, Asami T, Nishizawa N, Suzuki A, Kumano S, Terada M, Kusaka M, Kitada C, Ohtaki T. Chronic administration of the metastin/kisspeptin analog KISS1-305 or the investigational agent TAK-448 suppresses hypothalamic pituitary gonadal function and depletes plasma testosterone in adult male rats. Endocrinology. 2012 Nov;153(11):5297-308. doi: 10.1210/en.2012-1388. Epub 2012 Oct 1. PMID: 23027808.