Ono EI-601 | Human Neutrophil Elastase Inhibitor Metabolite | CAS#155023-59-9

MedKoo Cat#: 525789 | Name: Ono EI-601

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ono EI-601 is the main metabolite of the human neutrophil elastase inhibitor ONO-5046. In plasma and urine by direct injection column-switching HPLC proved to be useful for pharmacokinetic, toxicological and clinical studies.

Chemical Structure

Ono EI-601

CAS#155023-59-9

Theoretical Analysis

MedKoo Cat#: 525789

Name: Ono EI-601

CAS#: 155023-59-9

Chemical Formula: C15H14N2O6S

Exact Mass: 350.0573

Molecular Weight: 350.35

Elemental Analysis: C, 51.42; H, 4.03; N, 8.00; O, 27.40; S, 9.15

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Ono-EI-601; OnoEI601; Ono EI 601; Ono-EI 601; Ono EI-601

IUPAC/Chemical Name

2-(2-(4-hydroxyphenylsulfonamido)benzamido)acetic acid

InChi Key

QBMYNMQQDCMRPR-UHFFFAOYSA-N

InChi Code

InChI=1S/C15H14N2O6S/c18-10-5-7-11(8-6-10)24(22,23)17-13-4-2-1-3-12(13)15(21)16-9-14(19)20/h1-8,17-18H,9H2,(H,16,21)(H,19,20)

SMILES Code

O=C(O)CNC(C1=CC=CC=C1NS(=O)(C2=CC=C(O)C=C2)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 350.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Shintani T, Takamoto M, Sawada M, Aishita H, Nakagawa T. Simultaneous determination of human neutrophil elastase inhibitor (ONO-5046) and its metabolite in plasma and urine by direct injection column-switching HPLC. J Pharm Biomed Anal. 1994 Mar;12(3):397-405. PubMed PMID: 8031941.