Serazapine | CGS15040 | anxiolytic agent | 5-HT2 receptor antagonist | CAS#115313-22-9

MedKoo Cat#: 126221 | Name: Serazapine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Serazapine (CGS15040) is an anxiolytic agent. It is structurally novel 5-HT2 receptor antagonist.

Chemical Structure

Serazapine

CAS#115313-22-9 (free base)

Theoretical Analysis

MedKoo Cat#: 126221

Name: Serazapine

CAS#: 115313-22-9 (free base)

Chemical Formula: C22H23N3O2

Exact Mass: 361.1790

Molecular Weight: 361.45

Elemental Analysis: C, 73.11; H, 6.41; N, 11.63; O, 8.85

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

117581-05-2 (HCl) 115313-22-9 (free base)

Synonym

Serazapine; CPDD-0035; CGS15040; CPDD0035; CPDD 0035

IUPAC/Chemical Name

methyl 2-methyl-1,3,4,16b-tetrahydro-2H,10H-benzo[5,6]pyrazino[2',1':3,4][1,4]diazepino[1,2-a]indole-16-carboxylate

InChi Key

WPGUWABWNUSPMW-UHFFFAOYSA-N

InChi Code

InChI=1S/C22H23N3O2/c1-23-11-12-24-17-9-5-3-7-15(17)13-25-18-10-6-4-8-16(18)20(22(26)27-2)21(25)19(24)14-23/h3-10,19H,11-14H2,1-2H3

SMILES Code

COC(=O)C1=C2C3CN(C)CCN3C4=CC=CC=C4CN2C5=C1C=CC=C5

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 361.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Luders RC, Brunner LA, Shum LY, Ross HD, Das H. Determination of CGS 15040A in human plasma by liquid chromatography. J Pharm Biomed Anal. 1991;9(4):351-5. doi: 10.1016/0731-7085(91)80205-n. PMID: 1680469. 2: Katz RJ, Landau PS, Lott M, Bystritsky A, Diamond B, Hoehn-Saric R, Rosenthal M, Weise C. Serotonergic (5-HT2) mediation of anxiety-therapeutic effects of serazepine in generalized anxiety disorder. Biol Psychiatry. 1993 Jul 1-15;34(1-2):41-4. doi: 10.1016/0006-3223(93)90254-b. PMID: 8104044.