MedKoo Cat#: 562606 | Name: Seriniquinone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Seriniquinone is a selective anticancer agent. It acts by inducing cell death via autophagocytosis and targeting the cancer-protective protein dermcidin.

Chemical Structure

Seriniquinone
CAS#22200-69-7

Theoretical Analysis

MedKoo Cat#: 562606

Name: Seriniquinone

CAS#: 22200-69-7

Chemical Formula: C20H8O4S

Exact Mass: 344.0100

Molecular Weight: 344.34

Elemental Analysis: C, 69.76; H, 2.34; O, 18.59; S, 9.31

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Seriniquinone;
IUPAC/Chemical Name
Dinaphtho[2,3-b;2',3'-d]thiophene-5,7,12,13-tetraone
InChi Key
PWUWIMAXHCTYJA-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H8O4S/c21-15-9-5-1-3-7-11(9)17(23)19-13(15)14-16(22)10-6-2-4-8-12(10)18(24)20(14)25-19/h1-8H
SMILES Code
O=C(C1=C2C(C3=O)=C(C(C4=C3C=CC=C4)=O)S1)C5=C(C=CC=C5)C2=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 344.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Trzoss L, Fukuda T, Costa-Lotufo LV, Jimenez P, La Clair JJ, Fenical W. Seriniquinone, a selective anticancer agent, induces cell death by autophagocytosis, targeting the cancer-protective protein dermcidin. Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14687-92. doi: 10.1073/pnas.1410932111. Epub 2014 Sep 30. PubMed PMID: 25271322; PubMed Central PMCID: PMC4205641.