BMS-587101 is an LFA-1 Small-Molecule antagonist that reduces inflammation and joint destruction in murine models of arthritis. In vitro, BMS-587101 inhibited LFA-1–mediated adhesion of T cells to endothelial cells, T cell proliferation, and Th1 cytokine production.
MedKoo Cat#: 524506
Name: BMS-587101
CAS#: 509083-77-6
Chemical Formula: C26H20Cl2N4O4S
Exact Mass: 554.0582
Molecular Weight: 555.43
Elemental Analysis: C, 56.22; H, 3.63; Cl, 12.77; N, 10.09; O, 11.52; S, 5.77
The following data is based on the product molecular weight 555.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
