MedKoo Cat#: 575323 | Name: Faropenem
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Faropenem is an orally active beta-lactam antibiotic belonging to the penem group. It is resistant to some forms of extended-spectrum beta-lactamase.

Chemical Structure

Faropenem
Faropenem
CAS#106560-14-9 (free acid)

Theoretical Analysis

MedKoo Cat#: 575323

Name: Faropenem

CAS#: 106560-14-9 (free acid)

Chemical Formula: C12H15NO5S

Exact Mass: 285.0671

Molecular Weight: 285.31

Elemental Analysis: C, 50.52; H, 5.30; N, 4.91; O, 28.04; S, 11.24

Price and Availability

Size Price Availability Quantity
250mg USD 450.00 2 Weeks
500mg USD 750.00 2 Weeks
1g USD 1,250.00 2 Weeks
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Synonym
Faropenem; Fropenem; ALP 201; ALP201; ALP-201; SUN-5555; SUN5555; SUN 5555; SY5555; SY-5555; SY 5555; Wy 49605; Wy 49605; Wy-49605
IUPAC/Chemical Name
(+)-(5R,6S)-6-((1R)-1-Hydroxyethyl)-7-oxo-3-((2R)-tetrahydro-2-furyl)-4-thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid
InChi Key
HGGAKXAHAYOLDJ-FHZUQPTBSA-N
InChi Code
InChI=1S/C12H15NO5S/c1-5(14)7-10(15)13-8(12(16)17)9(19-11(7)13)6-3-2-4-18-6/h5-7,11,14H,2-4H2,1H3,(H,16,17)/t5-,6-,7+,11-/m1/s1
SMILES Code
C[C@@H](O)[C@@H]1[C@H]2SC(=C(N2C1=O)C(=O)O)[C@H]3CCCO3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 285.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Woodcock JM, Andrews JM, Brenwald NP, Ashby JP, Wise R. The in-vitro activity of faropenem, a novel oral penem. J Antimicrob Chemother. 1997 Jan;39(1):35-43. PubMed PMID: 9044026. 2: Mortensen JE, Egleton JH. Comparative in vitro activity of furopenem against aerobic bacteria isolated from pediatric patients. Diagn Microbiol Infect Dis. 1995 Jul;22(3):301-6. PubMed PMID: 8565421. 3: Sewell D, Barry A, Allen S, Fuchs P, McLaughlin J, Pfaller M. Comparative antimicrobial activities of the penem WY-49605 (SUN5555) against recent clinical isolates from five U.S. medical centers. Antimicrob Agents Chemother. 1995 Jul;39(7):1591-5. PubMed PMID: 7492110; PubMed Central PMCID: PMC162787. 4: Fuchs PC, Barry AL, Sewell DL. Antibacterial activity of WY-49605 compared with those of six other oral agents and selection of disk content for disk diffusion susceptibility testing. Antimicrob Agents Chemother. 1995 Jul;39(7):1472-9. PubMed PMID: 7492088; PubMed Central PMCID: PMC162765. 5: Cormican MG, Jones RN. Evaluation of the in-vitro activity of furopenem (SY5555 or SUN5555) against respiratory tract pathogens and beta-lactamase producing bacteria. J Antimicrob Chemother. 1995 Apr;35(4):535-9. PubMed PMID: 7628987.