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MedKoo Cat#: 575324 | Name: Faropenem sodium hemipentahydrate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Faropenem sodium hemipentahydrate is an orally active beta-lactam antibiotic belonging to the penem group. It is resistant to some forms of extended-spectrum beta-lactamase.

Chemical Structure

Faropenem sodium hemipentahydrate
Faropenem sodium hemipentahydrate
CAS#158365-51-6 (sodium hemipentahydrate)

Theoretical Analysis

MedKoo Cat#: 575324

Name: Faropenem sodium hemipentahydrate

CAS#: 158365-51-6 (sodium hemipentahydrate)

Chemical Formula: C24H38N2Na2O15S2

Exact Mass: 0.0000

Molecular Weight: 704.67

Elemental Analysis: C, 40.91; H, 5.44; N, 3.98; Na, 6.53; O, 34.06; S, 9.10

Price and Availability

Size Price Availability Quantity
10mg USD 385.00 2 Weeks
25mg USD 750.00 2 Weeks
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Related CAS #
106560-14-9 (free acid) 122547-49-3 (sodium) 158365-51-6 (sodium hemipentahydrate)
Synonym
(+)-Faropenem sodium hemipentahydrate; Faropenem sodium hemipentahydrate; Faropenem sodium hydrate; ALP 201; ALP201; ALP-201; SUN-5555; SUN5555; SUN 5555; SY5555; SY-5555; SY 5555; Wy 49605; Wy 49605; Wy-49605
IUPAC/Chemical Name
(5R,6S)-6-((R)-1-Hydroxyethyl)-7-oxo-3-((R)-tetrahydrofuran-2-yl)-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, sodium salt hydrate(2:2:5)
InChi Key
MOGICMVNWAUWMK-CQWVCGMZSA-L
InChi Code
InChI=1S/2C12H15NO5S.2Na.5H2O/c2*1-5(14)7-10(15)13-8(12(16)17)9(19-11(7)13)6-3-2-4-18-6;;;;;;;/h2*5-7,11,14H,2-4H2,1H3,(H,16,17);;;5*1H2/q;;2*+1;;;;;/p-2/t5-,6-,7?,11?;5-,6-,7+,11-;;;;;;;/m11......./s1
SMILES Code
O=C(C(N12)=C([C@@H]3OCCC3)S[C@]2([H])[C@@H]([C@H](O)C)C1=O)[O-].O=C(C(N45)=C([C@@H]6OCCC6)SC5C([C@H](O)C)C4=O)[O-].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[Na+].[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 704.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Woodcock JM, Andrews JM, Brenwald NP, Ashby JP, Wise R. The in-vitro activity of faropenem, a novel oral penem. J Antimicrob Chemother. 1997 Jan;39(1):35-43. PubMed PMID: 9044026. 2: Mortensen JE, Egleton JH. Comparative in vitro activity of furopenem against aerobic bacteria isolated from pediatric patients. Diagn Microbiol Infect Dis. 1995 Jul;22(3):301-6. PubMed PMID: 8565421. 3: Sewell D, Barry A, Allen S, Fuchs P, McLaughlin J, Pfaller M. Comparative antimicrobial activities of the penem WY-49605 (SUN5555) against recent clinical isolates from five U.S. medical centers. Antimicrob Agents Chemother. 1995 Jul;39(7):1591-5. PubMed PMID: 7492110; PubMed Central PMCID: PMC162787. 4: Fuchs PC, Barry AL, Sewell DL. Antibacterial activity of WY-49605 compared with those of six other oral agents and selection of disk content for disk diffusion susceptibility testing. Antimicrob Agents Chemother. 1995 Jul;39(7):1472-9. PubMed PMID: 7492088; PubMed Central PMCID: PMC162765. 5: Cormican MG, Jones RN. Evaluation of the in-vitro activity of furopenem (SY5555 or SUN5555) against respiratory tract pathogens and beta-lactamase producing bacteria. J Antimicrob Chemother. 1995 Apr;35(4):535-9. PubMed PMID: 7628987.