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MedKoo Cat#: 565501 | Name: Faropenem Sodium
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Faropenem is an orally active beta-lactam antibiotic belonging to the penem group. It is resistant to some forms of extended-spectrum beta-lactamase. It is available for oral use.

Chemical Structure

Faropenem Sodium
Faropenem Sodium
CAS#122547-49-3 (sodium)

Theoretical Analysis

MedKoo Cat#: 565501

Name: Faropenem Sodium

CAS#: 122547-49-3 (sodium)

Chemical Formula: C12H14NNaO5S

Exact Mass: 0.0000

Molecular Weight: 307.30

Elemental Analysis: C, 46.90; H, 4.59; N, 4.56; Na, 7.48; O, 26.03; S, 10.43

Price and Availability

Size Price Availability Quantity
10mg USD 350.00 2 Weeks
25mg USD 650.00 2 Weeks
50mg USD 950.00 2 Weeks
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Related CAS #
106560-14-9 (free acid) 122547-49-3 (sodium) 158365-51-6 (sodium hemipentahydrate)
Synonym
Faropenem Sodium; Furopenem; Fropenem sodium; Farom; Fropenum sodium; ALP 201; ALP201; ALP-201; SUN-5555; SUN5555; SUN 5555; SY5555; SY-5555; SY 5555; Wy 49605; Wy 49605; Wy-49605
IUPAC/Chemical Name
sodium (5R,6S)-6-((R)-1-hydroxyethyl)-7-oxo-3-((R)-tetrahydrofuran-2-yl)-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
InChi Key
ICSAXRANXQSPQP-VUKDEKJYSA-M
InChi Code
InChI=1S/C12H15NO5S.Na/c1-5(14)7-10(15)13-8(12(16)17)9(19-11(7)13)6-3-2-4-18-6;/h5-7,11,14H,2-4H2,1H3,(H,16,17);/q;+1/p-1/t5-,6-,7+,11-;/m1./s1
SMILES Code
C[C@@H](O)[C@@H]1[C@]2([H])N(C(C([O-])=O)=C([C@H]3CCCO3)S2)C1=O.[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 307.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Woodcock JM, Andrews JM, Brenwald NP, Ashby JP, Wise R. The in-vitro activity of faropenem, a novel oral penem. J Antimicrob Chemother. 1997 Jan;39(1):35-43. PubMed PMID: 9044026. 2: Mortensen JE, Egleton JH. Comparative in vitro activity of furopenem against aerobic bacteria isolated from pediatric patients. Diagn Microbiol Infect Dis. 1995 Jul;22(3):301-6. PubMed PMID: 8565421. 3: Sewell D, Barry A, Allen S, Fuchs P, McLaughlin J, Pfaller M. Comparative antimicrobial activities of the penem WY-49605 (SUN5555) against recent clinical isolates from five U.S. medical centers. Antimicrob Agents Chemother. 1995 Jul;39(7):1591-5. PubMed PMID: 7492110; PubMed Central PMCID: PMC162787. 4: Fuchs PC, Barry AL, Sewell DL. Antibacterial activity of WY-49605 compared with those of six other oral agents and selection of disk content for disk diffusion susceptibility testing. Antimicrob Agents Chemother. 1995 Jul;39(7):1472-9. PubMed PMID: 7492088; PubMed Central PMCID: PMC162765. 5: Cormican MG, Jones RN. Evaluation of the in-vitro activity of furopenem (SY5555 or SUN5555) against respiratory tract pathogens and beta-lactamase producing bacteria. J Antimicrob Chemother. 1995 Apr;35(4):535-9. PubMed PMID: 7628987. 6: Harada Y, Matsumoto T, Tsuji Y, Gondou I, Kobayashi N, Hayashi K, Uchida T, Uehara Y, Kido T, Fukuda T. [Pharmacokinetic and clinical studies on SY5555 dry syrup in children]. Jpn J Antibiot. 1995 Feb;48(2):261-70. Japanese. PubMed PMID: 7745815. 7: Motohiro T, Handa S, Yamada S, Oki S, Yoshinaga Y, Oda K, Sakata Y, Kato H, Yamashita F, Imai S, et al. [Pharmacokinetic, bacteriological and clinical studies of SY5555 in the pediatric field]. Jpn J Antibiot. 1995 Feb;48(2):238-60. Japanese. PubMed PMID: 7745814. 8: Wakiguchi H, Nagao A, Watanabe S, Okada T, Hamada F, Kurashige T. [Clinical and laboratory studies on SY5555 in pediatric infectious diseases]. Jpn J Antibiot. 1995 Feb;48(2):229-37. Japanese. PubMed PMID: 7745813. 9: Sekiguchi T, Okamoto T. [Clinical studies on SY5555 in pediatrics]. Jpn J Antibiot. 1995 Feb;48(2):220-8. Japanese. PubMed PMID: 7745812. 10: Furukawa S, Okada T. [A clinical evaluation of SY5555 in the treatment of pediatric infections]. Jpn J Antibiot. 1995 Feb;48(2):210-9. Japanese. PubMed PMID: 7745811. 11: Haruta T, Kobayashi Y. [Clinical study of SY5555 dry syrup in the pediatric field]. Jpn J Antibiot. 1995 Feb;48(2):205-9. Japanese. PubMed PMID: 7745810. 12: Kino M, Higashino H, Kobayashi Y. [Clinical evaluation of a new oral penem, SY5555, in infants and children]. Jpn J Antibiot. 1995 Feb;48(2):200-4. Japanese. PubMed PMID: 7745809. 13: Nishimura T, Sugita K, Aoki S, Takagi M. [Bacteriological and clinical studies of SY5555 in pediatric field]. Jpn J Antibiot. 1995 Feb;48(2):191-9. Japanese. PubMed PMID: 7745808. 14: Yokota T, Akita H, Sato Y, Iwata S, Sunakawa K. [Fundamental and clinical studies of SY5555 in pediatrics]. Jpn J Antibiot. 1995 Jan;48(1):92-102. Japanese. PubMed PMID: 7699847. 15: Toyonaga Y, Ishihara T, Tezuka T, Nakamura H. [Bacteriological, pharmacokinetic and clinical studies of SY5555 dry syrup in the pediatric field]. Jpn J Antibiot. 1995 Jan;48(1):71-91. Japanese. PubMed PMID: 7699846. 16: Niinou K, Sigeta M, Kuwahata K, Suzuki H, Sato H. [Clinical studies on SY5555 in pediatric infections]. Jpn J Antibiot. 1995 Jan;48(1):49-70. Japanese. PubMed PMID: 7699845. 17: Meguro H, Fujii R, Terashima I. [Clinical evaluation of a new oral penem, SY5555, in the pediatric field]. Jpn J Antibiot. 1995 Jan;48(1):41-8. Japanese. PubMed PMID: 7699844. 18: Tajima T, Kobayashi M, Hata M, Negishi S, Kubota K, Iitsuka T, Hagiwara N, Kudou S, Nakayama T, Abe T. [Pharmacokinetic, bacteriological, and clinical studies on SY5555 in children]. Jpn J Antibiot. 1995 Jan;48(1):31-40. Japanese. PubMed PMID: 7699843. 19: Kitamura K, Ihara T, Kamiya H, Nakano T, Itoh M, Sakurai M. [Studies on SY5555 in the field of pediatrics]. Jpn J Antibiot. 1995 Jan;48(1):133-9. Japanese. PubMed PMID: 7699836. 20: Kuno K, Ogawa A, Hayakawa F, Miyajima Y, Takahashi H, Okumura A, Kato T, Itomi K. [Clinical studies on SY5555 in the field of pediatrics]. Jpn J Antibiot. 1995 Jan;48(1):129-32. Japanese. PubMed PMID: 7699835.