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MedKoo Cat#: 145043 | Name: ITF-1124

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ITF-1124 is a metabolite of [14C]-ITF-296.

Chemical Structure

ITF-1124
ITF-1124
CAS#143248-47-9

Theoretical Analysis

MedKoo Cat#: 145043

Name: ITF-1124

CAS#: 143248-47-9

Chemical Formula: C10H11NO3

Exact Mass: 193.0739

Molecular Weight: 193.20

Elemental Analysis: C, 62.17; H, 5.74; N, 7.25; O, 24.84

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
ITF-1124; ITF1124; ITF 1124
IUPAC/Chemical Name
3-(2-hydroxyethyl)-2,3-dihydro-4H-benzo[e][1,3]oxazin-4-one
InChi Key
OCGPULOAWIAZQS-UHFFFAOYSA-N
InChi Code
1S/C10H11NO3/c12-6-5-11-7-14-9-4-2-1-3-8(9)10(11)13/h1-4,12H,5-7H2
SMILES Code
OCCN1COC2=CC=CC=C2C1=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 193.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Giachetti C, Bertolino M, Canali S, Lombardini E, Monzani MV, Sala A, Zanolo G. Pharmacokinetic study in dogs and monkeys after single intravenous and oral administrations of [14C]-ITF-296. Eur J Drug Metab Pharmacokinet. 1998 Apr- Jun;23(2):239-50. doi: 10.1007/BF03189346. PMID: 9725488. 2: Monzani MV, Coltro G, Sala A, Sardina M. Pharmacokinetics of ITF 296 (Sinitrodil) a novel organic nitrate, in healthy volunteers. Eur J Pharm Sci. 1999 Feb;7(3):179-84. doi: 10.1016/s0928-0987(98)00026-8. PMID: 9845803. 3: Monzani MV, Coltro G, Jiritano L, Sala A. Pharmacokinetic profile of ITF 296 in rats and dogs. J Cardiovasc Pharmacol. 1995;26 Suppl 4:S67-71. PMID: 8839229. 4: Monzani MV, Coltro G, Jiritano L, Sala A. Simultaneous determination of ITF 296 and two metabolites in plasma by a validated HPLC method. Boll Chim Farm. 1997 Apr;136(4):382-8. PMID: 9281893. 5: Giachetti C, Bertolino M, Canali S, Lombardini E, Monzani MV, Sala A, Zanolo G. Pharmacokinetic study in rats after single intravenous and oral administrations of [14C]-ITF-296. Eur J Drug Metab Pharmacokinet. 1998 Apr- Jun;23(2):230-8. doi: 10.1007/BF03189345. PMID: 9725487.