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MedKoo Cat#: 575020 | Name: ARM-210

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ARM-210 was discontinued for commercial reasons.

Chemical Structure

ARM-210
CAS#1467605-57-7 (free base)

Theoretical Analysis

MedKoo Cat#: 575020

Name: ARM-210

CAS#: 1467605-57-7 (free base)

Chemical Formula: C18H19NO3S

Exact Mass: 329.1086

Molecular Weight: 329.41

Elemental Analysis: C, 65.63; H, 5.81; N, 4.25; O, 14.57; S, 9.73

Price and Availability

This product was removed for the commercial reasons.
Related CAS #
1467605-57-7 (free base) 1467606-11-6 (hemifumarate)
Synonym
ARM210; ARM 210; ARM-210; Rycal dmd; S48168; S 48168; S-48168
IUPAC/Chemical Name
Benzoic acid, 4-((2,3-dihydro-7-methoxy-1,4-benzothiazepin-4(5H)-yl)methyl)-
InChi Key
JIGDAUOKKYKRKO-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H19NO3S/c1-22-16-6-7-17-15(10-16)12-19(8-9-23-17)11-13-2-4-14(5-3-13)18(20)21/h2-7,10H,8-9,11-12H2,1H3,(H,20,21)
SMILES Code
O=C(O)C1=CC=C(CN2CCSC3=CC=C(OC)C=C3C2)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 329.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Capogrosso RF, Mantuano P, Uaesoontrachoon K, Cozzoli A, Giustino A, Dow T, Srinivassane S, Filipovic M, Bell C, Vandermeulen J, Massari AM, De Bellis M, Conte E, Pierno S, Camerino GM, Liantonio A, Nagaraju K, De Luca A. Ryanodine channel complex stabilizer compound S48168/ARM210 as a disease modifier in dystrophin-deficient mdx mice: proof-of-concept study and independent validation of efficacy. FASEB J. 2018 Feb;32(2):1025-1043. doi: 10.1096/fj.201700182RRR. Epub 2018 Jan 3. PMID: 29097503; PMCID: PMC5888399.

View History

MLS-0390982

MLS-0390982