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MedKoo Cat#: 564886 | Name: BMPPB-32

Description:

WARNING: This product is for research use only, not for human or veterinary use.

BMPPB-32 is a highly selective LRRK2 inhibitor.

Chemical Structure

BMPPB-32
BMPPB-32
CAS#NONE

Theoretical Analysis

MedKoo Cat#: 564886

Name: BMPPB-32

CAS#: NONE

Chemical Formula: C24H26N4O2

Exact Mass: 402.2056

Molecular Weight: 402.50

Elemental Analysis: C, 71.62; H, 6.51; N, 13.92; O, 7.95

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
BMPPB32; BMPPB 32; BMPPB-32
IUPAC/Chemical Name
2-Benzyloxy-5-(4-methyl-piperazin-1-yl)-N-pyridin-3-yl-benzamide
InChi Key
QGEBKIOJSNPDFE-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H26N4O2/c1-27-12-14-28(15-13-27)21-9-10-23(30-18-19-6-3-2-4-7-19)22(16-21)24(29)26-20-8-5-11-25-17-20/h2-11,16-17H,12-15,18H2,1H3,(H,26,29)
SMILES Code
O=C(NC1=CC=CN=C1)C2=CC(N3CCN(C)CC3)=CC=C2OCC4=CC=CC=C4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 402.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Cording AC, Shiaelis N, Petridi S, Middleton CA, Wilson LG, Elliott CJH. Targeted kinase inhibition relieves slowness and tremor in a Drosophila model of LRRK2 Parkinson's disease. NPJ Parkinsons Dis. 2017 Dec 4;3:34. doi: 10.1038/s41531-017-0036-y. eCollection 2017. PubMed PMID: 29214211; PubMed Central PMCID: PMC5715132. 2: Afsari F, Christensen KV, Smith GP, Hentzer M, Nippe OM, Elliott CJ, Wade AR. Abnormal visual gain control in a Parkinson's disease model. Hum Mol Genet. 2014 Sep 1;23(17):4465-78. doi: 10.1093/hmg/ddu159. Epub 2014 Apr 9. PubMed PMID: 24718285; PubMed Central PMCID: PMC4119403.