IUPAC/Chemical Name
1,1'-(Oxydimethylene)bis(4-formylpyridinium) diiodide dioxime
InChi Key
MLAAVDSBLFBFQX-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H14N4O3.2HI/c19-15-9-13-1-5-17(6-2-13)11-21-12-18-7-3-14(4-8-18)10-16-20;;/h1-10H,11-12H2;2*1H
SMILES Code
O/N=C/C1=CC=[N+](COC[N+]2=CC=C(/C=N/O)C=C2)C=C1.[I-].[I-]
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
542.12
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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6: Worek F, Eyer P. The liberation of thiocholine from acetylthiocholine (ASCh) by pralidoxime iodide (2=PAM) and other oximes (obidoxime and diacetylmonoxime). Toxicol Lett. 2006 Dec 15;167(3):256-7; author reply 258. Epub 2006 Oct 20. PubMed PMID: 17113251.
7: Sakurada K, Ikegaya H, Ohta H, Akutsu T, Takatori T. Hydrolysis of an acetylthiocholine by pralidoxime iodide (2-PAM). Toxicol Lett. 2006 Oct 25;166(3):255-60. Epub 2006 Aug 12. PubMed PMID: 16971069.
8: Das Gupta S, Ghosh AK. Antidotal efficacy of isopropamide iodide in acute fluostigmine poisoning in mice. Pharmazie. 1985 Jul;40(7):499-500. PubMed PMID: 2864706.
9: Ramisz A, Szańkowska Z. Effect of E 600 and Toxobidin on the behavious of cholinesterases in mouse skeletal muscles in the course of experimental trichinellosis. Folia Histochem Cytochem (Krakow). 1976;14(4):321-6. PubMed PMID: 799612.
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