MedKoo Cat#: 531992 | Name: JYL1421
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

JYL1421 is a TRPV1 receptor antagonist.

Chemical Structure

JYL1421
JYL1421
CAS# 401907-26-4

Theoretical Analysis

MedKoo Cat#: 531992

Name: JYL1421

CAS#: 401907-26-4

Chemical Formula: C20H26FN3O2S2

Exact Mass: 423.1450

Molecular Weight: 423.57

Elemental Analysis: C, 56.71; H, 6.19; F, 4.49; N, 9.92; O, 7.55; S, 15.14

Price and Availability

Size Price Availability Quantity
5mg USD 380.00
10mg USD 650.00 2 Weeks
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Related CAS #
No Data
Synonym
JYL1421; JYL 1421; JYL-1421.
IUPAC/Chemical Name
3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-methanesulfonamidophenyl)methyl]thiourea
InChi Key
DUHBVFMCIJLUJX-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H26FN3O2S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)23-13-15-7-10-18(17(21)11-15)24-28(4,25)26/h5-11,24H,12-13H2,1-4H3,(H2,22,23,27)
SMILES Code
S=C(NCC1=CC=C(C(C)(C)C)C=C1)NCC2=CC=C(NS(=O)(C)=O)C(F)=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 423.57 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Jakab B, Helyes Z, Varga A, Bölcskei K, Szabó A, Sándor K, Elekes K, Börzsei R, Keszthelyi D, Pintér E, Petho G, Németh J, Szolcsányi J. Pharmacological characterization of the TRPV1 receptor antagonist JYL1421 (SC0030) in vitro and in vivo in the rat. Eur J Pharmacol. 2005 Jul 4;517(1-2):35-44. PubMed PMID: 15978575.