MedKoo Cat#: 341476 | Name: Xylazine hydrochloride
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Xylazine is an analogue of clonidine and an agonist at the α2 class of adrenergic receptor. It is used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle and other non-human mammals. Veterinarians also use xylazine as an emetic, especially in cats.

Chemical Structure

Xylazine hydrochloride
Xylazine hydrochloride
CAS#23076-35-9 (HCl)

Theoretical Analysis

MedKoo Cat#: 341476

Name: Xylazine hydrochloride

CAS#: 23076-35-9 (HCl)

Chemical Formula: C12H17ClN2S

Exact Mass: 256.0801

Molecular Weight: 256.79

Elemental Analysis: C, 56.13; H, 6.67; Cl, 13.80; N, 10.91; S, 12.48

Price and Availability

Size Price Availability Quantity
5g USD 450.00
10g USD 650.00
25g USD 950.00
100g USD 1,950.00
1kg USD 5,950.00
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Synonym
Xylazine hydrochloride; BAY-VA 1470; Anased; BAY 1470; BAY1470; BAY-1470; Primazine; Rometar; Sedomin; WH 7286; Xilazina
IUPAC/Chemical Name
4H-1,3-Thiazin-2-amine, N-(2,6-dimethylphenyl)-5,6-dihydro-, monohydrochloride
InChi Key
QYEFBJRXKKSABU-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H16N2S.ClH/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12;/h3,5-6H,4,7-8H2,1-2H3,(H,13,14);1H
SMILES Code
CC1=C(NC2=NCCCS2)C(C)=CC=C1.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 256.79 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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GYY4137, an Extended-Release Hydrogen Sulfide Donor, Reduces NMDA-Induced Neuronal Injury in the Murine Retina. Biol Pharm Bull. 2018;41(4):657-660. doi: 10.1248/bpb.b17-01032. PubMed PMID: 29607941. 8: Celiker FB, Tumkaya L, Yilmaz A, Coskun ZO, Celiker M, Oghan F, Mercantepe T, Terzi S, Dursun E. Effects of gadolinium-based contrast agents on submandibular gland tissue in rats. Eur Arch Otorhinolaryngol. 2018 Mar 31. doi: 10.1007/s00405-018-4959-7. [Epub ahead of print] PubMed PMID: 29605866. 9: Bezdudnaya T, Hormigo KM, Marchenko V, Lane MA. Spontaneous respiratory plasticity following unilateral high cervical spinal cord injury in behaving rats. Exp Neurol. 2018 Mar 26;305:56-65. doi: 10.1016/j.expneurol.2018.03.014. [Epub ahead of print] PubMed PMID: 29596845. 10: Ida KK, Sauvage A, Gougnard A, Grauwels M, Serteyn D, Sandersen C. Use of Nasotracheal Intubation during General Anesthesia in Two Ponies with Tracheal Collapse. Front Vet Sci. 2018 Mar 13;5:42. doi: 10.3389/fvets.2018.00042. eCollection 2018. PubMed PMID: 29594157; PubMed Central PMCID: PMC5859214. 11: Haan JD, Hay Kraus BL, Sathe SR. A comparison of the effects of carbon dioxide and medical air for abdominal insufflation on respiratory parameters in xylazine-sedated sheep undergoing laparoscopic artificial insemination. N Z Vet J. 2018 Apr 25:1-5. doi: 10.1080/00480169.2018.1458661. [Epub ahead of print] PubMed PMID: 29591780. 12: Lucas Castillo JA, Gozalo-Marcilla M, Werneck Fonseca M, Possebon FS, da Rosa AC, de Araujo Aguiar AJ. Sedative and cardiorespiratory effects of low doses of xylazine with and without acepromazine in Nordestino donkeys. Equine Vet J. 2018 Mar 22. doi: 10.1111/evj.12835. [Epub ahead of print] PubMed PMID: 29569401. 13: Sahu S, Li R, Kadeyala PK, Liu S, Schachner M. The human natural killer-1 (HNK-1) glycan mimetic ursolic acid promotes functional recovery after spinal cord injury in mouse. J Nutr Biochem. 2018 Feb 9;55:219-228. doi: 10.1016/j.jnutbio.2018.01.016. [Epub ahead of print] PubMed PMID: 29567576. 14: Smith JS, Sheley M, Chigerwe M. ASPIRATION PNEUMONIA IN TWO TIBETAN YAK BULLS ( BOS GRUNNIENS) AS A COMPLICATION OF KETAMINE-XYLAZINE-BUTORPHANOL ANESTHESIA FOR RECUMBENT CASTRATION. J Zoo Wildl Med. 2018 Mar;49(1):242-246. doi: 10.1638/2016-0205R1.1. PubMed PMID: 29517446. 15: Hibbs CD, Barrett PM, Dees DD. Intraocular pressure reference intervals in eyes of clinically normal miniature donkeys (Equus africanus asinus). Vet Ophthalmol. 2018 Mar 8. doi: 10.1111/vop.12561. [Epub ahead of print] PubMed PMID: 29517162. 16: Seo EH, Song GY, Namgung JH, Oh CS, Lee SH, Kim SH. Receptor for activated C kinase 1 in rats with ischemia-reperfusion injury: intravenous versus inhalation anaesthetic agents. Int J Med Sci. 2018 Feb 12;15(4):352-358. doi: 10.7150/ijms.22591. eCollection 2018. PubMed PMID: 29511370; PubMed Central PMCID: PMC5835705. 17: Tighe RM, Birukova A, Yeager MJ, Reece SW, Gowdy KM. Euthanasia and Lavage Mediated Effects on Bronchoalveolar Measures of Lung Injury and Inflammation. Am J Respir Cell Mol Biol. 2018 Feb 26. doi: 10.1165/rcmb.2017-0357OC. [Epub ahead of print] PubMed PMID: 29481287. 18: Fulkerson CV, Lim CK, Baird AN, Weil AB, Heng HG, Gutierrez-Crespo B, Moore GE. Optimized computed tomography protocol for assessment of dentition in alpacas. Am J Vet Res. 2018 Mar;79(3):311-316. doi: 10.2460/ajvr.79.3.311. PubMed PMID: 29466047. 19: Tsukamoto A, Niino N, Sakamoto M, Ohtani R, Inomata T. The validity of anesthetic protocols for the surgical procedure of castration in rats. Exp Anim. 2018 Feb 14. doi: 10.1538/expanim.18-0003. [Epub ahead of print] PubMed PMID: 29445064. 20: Wittenberg-Voges L, Kästner SB, Raekallio M, Vainio OM, Rohn K, Hopster K. Effect of dexmedetomidine and xylazine followed by MK-467 on gastrointestinal microperfusion in anaesthetized horses. Vet Anaesth Analg. 2018 Mar;45(2):165-174. doi: 10.1016/j.vaa.2017.08.010. Epub 2017 Sep 15. PubMed PMID: 29439859.