Synonym
Xylazine; BAY-VA 1470; Anased; BAY 1470; BAY1470; BAY-1470; Primazine; Rometar; Sedomin; WH 7286; Xilazina
IUPAC/Chemical Name
N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine
InChi Key
BPICBUSOMSTKRF-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H16N2S/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12/h3,5-6H,4,7-8H2,1-2H3,(H,13,14)
SMILES Code
2,6-Xylidine, N-(5,6-dihydro-4H-1,3-thiazinyl)-
Appearance
White to off-white crystalline powder.
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
220.33
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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6: Capraro AJ, Wiley JF 2nd, Tucker JR. Severe intoxication from xylazine inhalation. Pediatr Emerg Care. 2001 Dec;17(6):447-8. Review. PubMed PMID: 11753193.
7: Hoffmann U, Meister CM, Golle K, Zschiesche M. Severe intoxication with the veterinary tranquilizer xylazine in humans. J Anal Toxicol. 2001 May-Jun;25(4):245-9. Review. PubMed PMID: 11386637.
8: Chamberlain PL, Brynes SD. The regulatory status of xylazine for use in food-producing animals in the United States. J Vet Pharmacol Ther. 1998 Aug;21(4):322-9. Review. PubMed PMID: 9731956.
9: Schmidt-Oechtering GU, Becker K. [Old and new alpha 2-adrenoceptor agonists. 1. Xylazine and medetomidine]. Tierarztl Prax. 1992 Oct;20(5):447-58. Review. German. PubMed PMID: 1359676.
10: Gallanosa AG, Spyker DA, Shipe JR, Morris DL. Human xylazine overdose: a comparative review with clonidine, phenothiazines, and tricyclic antidepressants. Clin Toxicol. 1981 Jun;18(6):663-78. Review. PubMed PMID: 6115734.
11: Holmes AM, Clark WT. Xylazine for sedation of horses. N Z Vet J. 1977 Jun;25(6):159-61. Review. PubMed PMID: 351482.
