MedKoo Cat#: 561141 | Name: Alpha-Tocopherol phosphate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Alpha-Tocopherol phosphate is a vascular endothelial growth factor (VEGF) expression inducer. Alpha-Tocopherol phosphate stimulates PI3Kγ activity by stimulating hTAP-mediated phosphatidylinositol exchange and presentation to the enzyme and/or dissociation of an inactive heterodimer.

Chemical Structure

Alpha-Tocopherol phosphate
Alpha-Tocopherol phosphate
CAS#38976-17-9 (phosphate)

Theoretical Analysis

MedKoo Cat#: 561141

Name: Alpha-Tocopherol phosphate

CAS#: 38976-17-9 (phosphate)

Chemical Formula: C29H51O5P

Exact Mass: 510.3474

Molecular Weight: 510.70

Elemental Analysis: C, 68.20; H, 10.07; O, 15.66; P, 6.07

Price and Availability

Size Price Availability Quantity
10mg USD 350.00 2 Weeks
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Synonym
Alpha-Tocopherol phosphate; Alpha Tocopherol phosphate; Alphatocopherol phosphate; TocP; Vtamin E phosphate; αTP; α TP; α-TP; α-Tocopherol phosphate
IUPAC/Chemical Name
[(2R)-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] dihydrogen phosphate
InChi Key
JUIUXBHZFNHITF-IEOSBIPESA-N
InChi Code
InChI=1S/C29H51O5P/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(34-35(30,31)32)23(5)24(6)28(26)33-29/h20-22H,9-19H2,1-8H3,(H2,30,31,32)/t21-,22-,29-/m1/s1
SMILES Code
O=P(O)(OC1=C(C)C(CC[C@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)O2)=C2C(C)=C1C)O
Appearance
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 510.70 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zingg JM, Meydani M, Azzi A. alpha-Tocopheryl phosphate--an active lipid mediator? Mol Nutr Food Res. 2010 May;54(5):679-92. doi: 10.1002/mnfr.200900404. Review. PubMed PMID: 20169583. 2: Birringer M. Analysis of vitamin E metabolites in biological specimen. Mol Nutr Food Res. 2010 May;54(5):588-98. doi: 10.1002/mnfr.200900457. Review. PubMed PMID: 20169585. 3: Zingg JM, Meydani M, Azzi A. α-Tocopheryl phosphate--an activated form of vitamin E important for angiogenesis and vasculogenesis? Biofactors. 2012 Jan-Feb;38(1):24-33. doi: 10.1002/biof.198. Epub 2012 Jan 27. Review. PubMed PMID: 22281871.