Clinafloxacin hydrochloride | CAS#105956-99-8 | Antibacterial Agent

MedKoo Cat#: 524756 | Name: Clinafloxacin hydrochloride

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Clinafloxacin is an antimicrobial antibiotic that displays broad-spectrum antibacterial activity against Gram-positive, Gram-negative, and anaerobic pathogens by inhibiting the bacterial regulatory enzyme DNA gyrase (IC50 = 0.92 µg/ml) as well as topoisomerase IV (IC50 = 1.62 µg/ml).

Chemical Structure

Clinafloxacin hydrochloride

CAS#105956-99-8 (HCl)

Theoretical Analysis

MedKoo Cat#: 524756

Name: Clinafloxacin hydrochloride

CAS#: 105956-99-8 (HCl)

Chemical Formula: C17H18Cl2FN3O3

Exact Mass: 0.0000

Molecular Weight: 402.25

Elemental Analysis: C, 50.76; H, 4.51; Cl, 17.63; F, 4.72; N, 10.45; O, 11.93

Price and Availability

Size	Price	Availability
100mg	USD 450.00	2 Weeks
250mg	USD 850.00	2 Weeks
500mg	USD 1,250.00	2 Weeks
1g	USD 1,850.00	2 Weeks

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Related CAS #

105956-97-6 (free base) 105956-99-8 (HCl)

Synonym

Clinafloxacin hydrochloride; Clinafloxacin HCl; UNII-G17M59V0FY; CI-960 HCl; CI 960 HCl; CI960 HCl; KR 11095; KR11095; KR-11095; AM 1091; AM1091; AM-1091

IUPAC/Chemical Name

7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride

InChi Key

BMACYHMTJHBPOX-UHFFFAOYSA-N

InChi Code

InChI=1S/C17H17ClFN3O3.ClH/c18-13-14-10(5-12(19)15(13)21-4-3-8(20)6-21)16(23)11(17(24)25)7-22(14)9-1-2-9;/h5,7-9H,1-4,6,20H2,(H,24,25);1H

SMILES Code

ClC1=C2N(C3CC3)C=C(C(C2=CC(F)=C1N4CC(CC4)N)=O)C(O)=O.Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 402.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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