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MedKoo Cat#: 561557 | Name: SFOM-0046

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SFOM-0046 is an anticancer agent. It arrests the cell cycle in S-phase and causes DNA replication stress, leading to the phosphorylation of H2AX into gamma-H2AX.

Chemical Structure

SFOM-0046
SFOM-0046
CAS#1383607-61-1

Theoretical Analysis

MedKoo Cat#: 561557

Name: SFOM-0046

CAS#: 1383607-61-1

Chemical Formula: C17H20N2O4S

Exact Mass: 348.1144

Molecular Weight: 348.41

Elemental Analysis: C, 58.60; H, 5.79; N, 8.04; O, 18.37; S, 9.20

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
SFOM-0046; SFOM 0046; SFOM0046;
IUPAC/Chemical Name
2-Ethylphenyl 4-(3-ethylureido)benzenesulfonate
InChi Key
BEQRKSLOFGBOPF-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H20N2O4S/c1-3-13-7-5-6-8-16(13)23-24(21,22)15-11-9-14(10-12-15)19-17(20)18-4-2/h5-12H,3-4H2,1-2H3,(H2,18,19,20)
SMILES Code
O=S(C1=CC=C(NC(NCC)=O)C=C1)(OC2=CC=CC=C2CC)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 348.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Pauty J, Côté MF, Rodrigue A, Velic D, Masson JY, Fortin S. Investigation of the DNA damage response to SFOM-0046, a new small-molecule drug inducing DNA double-strand breaks. Sci Rep. 2016 Mar 22;6:23302. doi: 10.1038/srep23302. PubMed PMID: 27001483; PubMed Central PMCID: PMC4802344.

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SG2057

SG2057