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MedKoo Cat#: 577986 | Name: Songorine hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Songorine hydrochloride is a biochemical.

Chemical Structure

Songorine hydrochloride
Songorine hydrochloride
CAS#51064-89-2

Theoretical Analysis

MedKoo Cat#: 577986

Name: Songorine hydrochloride

CAS#: 51064-89-2

Chemical Formula: C22H32ClNO3

Exact Mass: 393.2071

Molecular Weight: 393.95

Elemental Analysis: C, 67.07; H, 8.19; Cl, 9.00; N, 3.56; O, 12.18

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Bullatine G hydrochloride; Bullatine G HCl; Napellonine hydrochloride; Napellonine HCl; Songorine hydrochloride; Songorine HCl
IUPAC/Chemical Name
(3R,6S,6aR,6bR,9R,11R,11aR,12R,12aR,14R)-1-ethyl-6,11-dihydroxy-3-methyl-10-methylenedodecahydro-3,6a,12-(epiethane[1,1,2]triyl)-9,11a-methanoazuleno[2,1-b]azocin-8(9H)-one hydrochloride
InChi Key
OBBXHDIDARFQEV-SRVKNAIVSA-N
InChi Code
InChI=1S/C22H31NO3.ClH/c1-4-23-10-20(3)6-5-17(25)22-15(20)7-13(18(22)23)21-9-12(11(2)19(21)26)14(24)8-16(21)22;/h12-13,15-19,25-26H,2,4-10H2,1,3H3;1H/t12-,13+,15-,16-,17+,18-,19-,20+,21+,22+;/m1./s1
SMILES Code
Cl.CCN1C[C@]2(C)CC[C@H](O)[C@@]34[C@@H]2C[C@@H]([C@@H]13)[C@@]56C[C@@H](C(=O)C[C@@H]45)C(=C)[C@H]6O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 393.95 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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PubMed PMID: 27624993. 8: Ji X, Liu H, An C, Wang Y, Zhao H, Zhang Q, Li M, Qi F, Chen Z, Wang X, Wang L. You-Gui pills promote nerve regeneration by regulating netrin1, DCC and Rho family GTPases RhoA, Racl, Cdc42 in C57BL/6 mice with experimental autoimmune encephalomyelitis. J Ethnopharmacol. 2016 Jul 1;187:123-33. doi: 10.1016/j.jep.2016.04.025. Epub 2016 Apr 20. PubMed PMID: 27106785. 9: Zhang DK, Han X, Li RY, Niu M, Zhao YL, Wang JB, Yang M, Xiao XH. [Analysis on characteristic constituents of crude Aconitum carmichaelii in different regions based on UPLC-Q-TOF-MS]. Zhongguo Zhong Yao Za Zhi. 2016 Feb;41(3):463-469. doi: 10.4268/cjcmm20160318. Chinese. PubMed PMID: 28868865. 10: Zyuz'kov GN, Zhdanov VV, Udut EV, Miroshnichenko LA, Chaikovskii AV, Simanina EV, Udut VV, Stavrova LA, Polyakova TY, Minakova MY, Trifonova OY, Gridneva TD, Dygai AM. Role of JNK and Involvement of p53 in Stimulation of Growth Potential Realization of Mesenchymal Precursor Cells by Alkaloid Songorine. Bull Exp Biol Med. 2015 Nov;160(1):64-7. doi: 10.1007/s10517-015-3099-y. Epub 2015 Nov 25. PubMed PMID: 26608375. 11: Zyuz'kov GN, Zhdanov VV, Udut EV, Miroshnichenko LA, Chaikovskii AV, Simanina EV, Polyakova TY, Minakova MY, Udut VV, Tolstikova TG, Shul'ts EE, Stavrova LA, Burmina YV, Suslov NI, Dygai AM. Role of cAMP- and IKK-2-Dependent Signaling Pathways in Functional Stimulation of Mesenchymal Progenitor Cells with Alkaloid Songorine. Bull Exp Biol Med. 2015 Sep;159(5):642-5. doi: 10.1007/s10517-015-3036-0. Epub 2015 Oct 16. PubMed PMID: 26472093. 12: Nesterova YV, Povet'eva TN, Suslov NI, Shults EE, Ziuz'kov GN, Aksinenko SG, Afanas'eva OG, Krapivin AV, Kharina TG. Anxiolytic Activity of Diterpene Alkaloid Songorine. Bull Exp Biol Med. 2015 Sep;159(5):620-2. doi: 10.1007/s10517-015-3029-z. Epub 2015 Oct 15. PubMed PMID: 26468026. 13: Dong YY, Mao B, Guan H, Bai Y, Chi B, Shan YY, Lian QQ, Ge RS. Determination of songorine in rat plasma by UPLC-MS/MS: Assay development and application to pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 1;1002:234-8. doi: 10.1016/j.jchromb.2015.08.037. Epub 2015 Aug 28. PubMed PMID: 26342165. 14: Zyuz'kov GN, Zhdanov VV, Miroshnichenko LA, Udut EV, Chaikovskii AV, Simanina EV, Danilets MG, Minakova MY, Udut VV, Tolstikova TG, Shults EE, Stavrova LA, Burmina YV, Dygai AM. Involvement of PI3K, MAPK ERK1/2 and p38 in Functional Stimulation of Mesenchymal Progenitor Cells by Alkaloid Songorine. Bull Exp Biol Med. 2015 May;159(1):58-61. doi: 10.1007/s10517-015-2889-6. Epub 2015 Jun 2. PubMed PMID: 26033591. 15: Yang CL, Huang ZF, Zhang YH, Liu YH, Liu YH, Chen Y, Yi JH. [Effects of steaming and baking on content of alkaloids in Aconite Lateralis Radix (Fuzi)]. Zhongguo Zhong Yao Za Zhi. 2014 Dec;39(24):4798-803. Chinese. 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