MedKoo Cat#: 317184 | Name: Amlodipine
Featured New

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Amlodipine (as besylate, mesylate or maleate) is a medication used to lower blood pressure and prevent chest pain. It belongs to a group of medications known as dihydropyridine-type calcium channel blockers. By widening of blood vessels it lowers blood pressure. In angina, amlodipine increases blood flow to the heart muscle to relieve pain due to angina.

Chemical Structure

Amlodipine
Amlodipine
CAS#88150-42-9 (free base)

Theoretical Analysis

MedKoo Cat#: 317184

Name: Amlodipine

CAS#: 88150-42-9 (free base)

Chemical Formula: C20H25ClN2O5

Exact Mass: 408.1452

Molecular Weight: 408.88

Elemental Analysis: C, 58.75; H, 6.16; Cl, 8.67; N, 6.85; O, 19.57

Price and Availability

Size Price Availability Quantity
1g USD 250.00 Ready to ship
2g USD 400.00 Ready to ship
5g USD 650.00 Ready to ship
10g USD 950.00 Ready to ship
20g USD 1,450.00 Ready to ship
Bulk Inquiry
Buy Now
Add to Cart
Synonym
Amlodis; Norvasc; Amlocard; Coroval; UK-4834; UK4834; UK 4834
IUPAC/Chemical Name
(RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
InChi Key
HTIQEAQVCYTUBX-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3
SMILES Code
O=C(C1=C(COCCN)NC(C)=C(C(OC)=O)C1C2=CC=CC=C2Cl)OCC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Related: 88150-42-9 (Amlodipine) 111470-99-6 (Amlodipine besylate) 88150-47-4(Amlodipine maleate)
Certificate of Analysis
Safety Data Sheet (SDS)

Preparing Stock Solutions

The following data is based on the product molecular weight 408.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Gottwald-Hostalek U, Sun N, Barho C, Hildemann S. Management of Hypertension With a Fixed-Dose (Single-Pill) Combination of Bisoprolol and Amlodipine. Clin Pharmacol Drug Dev. 2017 Jan;6(1):9-18. doi: 10.1002/cpdd.309. Epub 2016 Oct 26. PubMed PMID: 27653022. 2: van Zwieten PA. Amlodipine: an overview of its pharmacodynamic and pharmacokinetic properties. Clin Cardiol. 1994 Sep;17(9 Suppl 3):III3-6. Review. PubMed PMID: 9156957.