Synonym
A4B17; A4 B17; A4-B17;
IUPAC/Chemical Name
2-(4-fluorophenyl)-5-(trifluoromethyl)benzo[d]thiazole
InChi Key
HVPGYAGVCOFPJH-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H7F4NS/c15-10-4-1-8(2-5-10)13-19-11-7-9(14(16,17)18)3-6-12(11)20-13/h1-7H
SMILES Code
FC(C1=CC=C(SC(C2=CC=C(F)C=C2)=N3)C3=C1)(F)F
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
297.27
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Kuznik NC, Solozobova V, Jung N, Gräßle S, Lei Q, Lewandowski EM, Munuganti R, Zoubeidi A, Chen Y, Bräse S, Cato ACB. Development of a Benzothiazole Scaffold-Based Androgen Receptor N-Terminal Inhibitor for Treating Androgen- Responsive Prostate Cancer. ACS Chem Biol. 2021 Nov 19;16(11):2103-2108. doi: 10.1021/acschembio.1c00390. Epub 2021 Sep 10. PMID: 34506104.
2: Tian J, Zhu L, Wang W, Zhang L, Li Z, Zhao Q, Xing K, Feng Z, Peng X. Genomic Analysis of Microbulbifer sp. Strain A4B-17 and the Characterization of Its Metabolic Pathways for 4-Hydroxybenzoic Acid Synthesis. Front Microbiol. 2018 Dec 18;9:3115. doi: 10.3389/fmicb.2018.03115. PMID: 30619190; PMCID: PMC6305291.
3: Peng X, Adachi K, Chen C, Kasai H, Kanoh K, Shizuri Y, Misawa N. Discovery of a marine bacterium producing 4-hydroxybenzoate and its alkyl esters, parabens. Appl Environ Microbiol. 2006 Aug;72(8):5556-61. doi: 10.1128/AEM.00494-06. PMID: 16885309; PMCID: PMC1538717.
