Amlodipine besylate, (R)- | CAS# 828247-64-9 | Biochemical

MedKoo Cat#: 573798 | Name: Amlodipine besylate, (R)-

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Amlodipine besylate, (R)- is a medication used to lower blood pressure and prevent chest pain.

Chemical Structure

Amlodipine besylate, (R)-

CAS#828247-64-9 ( besylate R-iso)

Theoretical Analysis

MedKoo Cat#: 573798

Name: Amlodipine besylate, (R)-

CAS#: 828247-64-9 ( besylate R-iso)

Chemical Formula: C26H31ClN2O8S

Exact Mass: 566.1490

Molecular Weight: 567.05

Elemental Analysis: C, 55.07; H, 5.51; Cl, 6.25; N, 4.94; O, 22.57; S, 5.65

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

88150-42-9 (free base) 103129-81-3 (free base R-iso) 526216-43-3 (adipate) 111470-99-6 (besylate) 532929-67-2 (besylate hydrate) 828247-64-9 ( besylate R-iso) 652969-01-2 (camsylate) 246852-09-5 (HBr) 246852-07-3 (HCl) 1027337-86-5 (HCl R-iso)

Synonym

Amlodipine besylate, (R)-

IUPAC/Chemical Name

3,5-Pyridinedicarboxylic acid, 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, (4R)-, benzenesulfonate (1:1)

InChi Key

ZPBWCRDSRKPIDG-UNTBIKODSA-N

InChi Code

1S/C20H25ClN2O5.C6H6O3S/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21;7-10(8,9)6-4-2-1-3-5-6/h5-8,17,23H,4,9-11,22H2,1-3H3;1-5H,(H,7,8,9)/t17-;/m1./s1

SMILES Code

CCOC(=O)C1=C(NC(=C([C@H]1c2ccccc2Cl)C(=O)OC)C)COCCN.c1ccc(cc1)S(=O)(=O)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 567.05 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Gottwald-Hostalek U, Sun N, Barho C, Hildemann S. Management of Hypertension With a Fixed-Dose (Single-Pill) Combination of Bisoprolol and Amlodipine. Clin Pharmacol Drug Dev. 2017 Jan;6(1):9-18. doi: 10.1002/cpdd.309. Epub 2016 Oct 26. PubMed PMID: 27653022. 2: van Zwieten PA. Amlodipine: an overview of its pharmacodynamic and pharmacokinetic properties. Clin Cardiol. 1994 Sep;17(9 Suppl 3):III3-6. Review. PubMed PMID: 9156957.