SRI-011381 HCl | CAS#2070014-88-7 | TGF-beta signaling antagonist

MedKoo Cat#: 128351 | Name: SRI-011381 HCl

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

SRI-011381 is an agonist of the TGF-beta signaling pathway for treatment of Alzheimer's disease. SRI-011381 can mitigate the effects of NRP1 knockdown on epithelial-mesenchymal transition (EMT) and ECM deposition.

Chemical Structure

SRI-011381 HCl

CAS#2070014-88-7 (HCl)

Theoretical Analysis

MedKoo Cat#: 128351

Name: SRI-011381 HCl

CAS#: 2070014-88-7 (HCl)

Chemical Formula: C20H32ClN3O

Exact Mass: 0.0000

Molecular Weight: 365.95

Elemental Analysis: C, 65.64; H, 8.81; Cl, 9.69; N, 11.48; O, 4.37

Price and Availability

Size	Price	Availability
5mg	USD 450.00	2 Weeks
25g	USD 950.00	2 Weeks
100mg	USD 1,650.00	2 Weeks

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Related CAS #

2070014-88-7 (HCl) 1629138-41-5 (free base)

Synonym

SRI-011381; SRI 011381; SRI011381; SRI-011381 hydrochloride; SRI-011381 HCl;

IUPAC/Chemical Name

1-benzyl-3-cyclohexyl-1-(piperidin-4-ylmethyl)urea hydrochloride

InChi Key

GPNMJVSGNMDOJN-UHFFFAOYSA-N

InChi Code

InChI=1S/C20H31N3O.ClH/c24-20(22-19-9-5-2-6-10-19)23(15-17-7-3-1-4-8-17)16-18-11-13-21-14-12-18;/h1,3-4,7-8,18-19,21H,2,5-6,9-16H2,(H,22,24);1H

SMILES Code

O=C(NC1CCCCC1)N(CC2=CC=CC=C2)CC3CCNCC3.Cl[H]

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 365.95 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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