Bamocaftor, also known as VX 659, is a CFTR channel (DeltaF508-CFTR Mutant) corrector in patients with Cystic Fibrosis who are homozygous for the F508del mutation of the CF transmembrane conductance regulator (CFTR) gene, or who are heterozygous for the F508del mutation and a minimal function (MF) CFTR mutation not likely to respond to tezacaftor, ivacaftor, or tezacaftor/ivacaftor and also in combination with tezacaftor and VX-561 in F508del/MF in patients with cystic fibrosis.
MedKoo Cat#: 124895
Name: Bamocaftor potassium
CAS#: 2204245-47-4 (potassium)
Chemical Formula: C28H31F3KN5O4S
Exact Mass: 629.1700
Molecular Weight: 629.74
Elemental Analysis: C, 53.40; H, 4.96; F, 9.05; K, 6.21; N, 11.12; O, 10.16; S, 5.09
The following data is based on the product molecular weight 629.74 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
