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MedKoo Cat#: 125929 | Name: Pipoxizine hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pipoxizine is a first-generation antihistamine as well as serotonin antagonist of the diphenylmethylpiperazine group related to hydroxyzine. It was investigated as a bronchodilator but was never marketed.

Chemical Structure

Pipoxizine hydrochloride
Pipoxizine hydrochloride
CAS#29958-58-5 (HCl)

Theoretical Analysis

MedKoo Cat#: 125929

Name: Pipoxizine hydrochloride

CAS#: 29958-58-5 (HCl)

Chemical Formula: C24H32ClNO3

Exact Mass: 417.2071

Molecular Weight: 417.97

Elemental Analysis: C, 68.97; H, 7.72; Cl, 8.48; N, 3.35; O, 11.48

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
29958-58-5 (HCl) 55837-21-3 (free base)
Synonym
Pipoxizine hydrochloride; Pipoxizine; Pipoxizina; Pipoxizinum
IUPAC/Chemical Name
2-(2-(2-(4-(diphenylmethylene)piperidin-1-yl)ethoxy)ethoxy)ethan-1-ol hydrochloride
InChi Key
PFVPKJFVMXJPGJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H31NO3.ClH/c26-16-18-28-20-19-27-17-15-25-13-11-23(12-14-25)24(21-7-3-1-4-8-21)22-9-5-2-6-10-22;/h1-10,26H,11-20H2;1H
SMILES Code
Cl.OCCOCCOCCN1CCC(CC1)=C(C2=CC=CC=C2)C3=CC=CC=C3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 417.97 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Neukirch F, Korobaeff M, Verdier F, Timsit G, Fay M, Drutel P. Action d'un aérosol d'histamine chez 20 sujets ayant une hyperréactivité histaminique. Application à l'étude de l'effect protecteur de la Pipoxizine [Effect of a histamine aerosol in 20 subjects with histamine hyperreactivity. Application to a study of the protective properties of pipoxizine]. Rev Inst Hyg Mines (Hasselt). 1978;33(4):191-5. French. PMID: 45187. 2: Verstraeten JM. Etude en double insu de l'action de la pipoxizine et du fénoterol administres par voie orale chez des malades bronchospastiques [Double blind cross over study with pipoxizine and fenoterol given orally on cord patients (author's transl)]. Acta Tuberc Pneumol Belg. 1978 Jul- Dec;69(3-4):247-55. French. PMID: 755372.