MedKoo Cat#: 414202 | Name: K201 free base

Description:

WARNING: This product is for research use only, not for human or veterinary use.

K201 free base is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Antiarrhythmic and cardioprotective properties.

Chemical Structure

K201 free base
K201 free base
CAS#145903-06-6 (free base)

Theoretical Analysis

MedKoo Cat#: 414202

Name: K201 free base

CAS#: 145903-06-6 (free base)

Chemical Formula: C25H32N2O2S

Exact Mass: 424.2184

Molecular Weight: 424.60

Elemental Analysis: C, 70.72; H, 7.60; N, 6.60; O, 7.54; S, 7.55

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Synonym
K201 free base; K 201 free base; K-201 free base
IUPAC/Chemical Name
3-(4-benzylpiperidin-1-yl)-1-(7-methoxy-2,3-dihydrobenzo[f][1,4]thiazepin-4(5H)-yl)propan-1-one
InChi Key
KCWGETCFOVJEPI-UHFFFAOYSA-N
InChi Code
InChI=1S/C25H32N2O2S/c1-29-23-7-8-24-22(18-23)19-27(15-16-30-24)25(28)11-14-26-12-9-21(10-13-26)17-20-5-3-2-4-6-20/h2-8,18,21H,9-17,19H2,1H3
SMILES Code
COc1cc2c(SCCN(C(CCN3CCC(CC3)Cc4ccccc4)=O)C2)cc1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 424.60 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL