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MedKoo Cat#: 576773 | Name: IS-741 sodium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

IS-741 sodium is a phospholipase A2 inhibitor.

Chemical Structure

IS-741 sodium
IS-741 sodium
CAS#141283-87-6

Theoretical Analysis

MedKoo Cat#: 576773

Name: IS-741 sodium

CAS#: 141283-87-6

Chemical Formula: C15H19F3N3NaO3S

Exact Mass: 401.0997

Molecular Weight: 401.38

Elemental Analysis: C, 44.89; H, 4.77; F, 14.20; N, 10.47; Na, 5.73; O, 11.96; S, 7.99

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
IS-741 sodium; IS 741 sodium; IS741 sodium
IUPAC/Chemical Name
Cyclohexanecarboxamide, N-(2-((ethylsulfonyl)amino)-5-(trifluoromethyl)-3-pyridinyl)-, monosodium salt
InChi Key
RVWHCCQDZKMPAZ-UHFFFAOYSA-M
InChi Code
InChI=1S/C15H20F3N3O3S.Na/c1-2-25(23,24)21-13-12(8-11(9-19-13)15(16,17)18)20-14(22)10-6-4-3-5-7-10;/h8-10H,2-7H2,1H3,(H2,19,20,21,22);/q;+1/p-1
SMILES Code
[Na+].CCS(=O)(=O)[N-]c1ncc(cc1NC(=O)C2CCCCC2)C(F)(F)F
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 401.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Garcia-Garcia HM, Serruys PW. Phospholipase A2 inhibitors. Curr Opin Lipidol. 2009 Aug;20(4):327-32. doi: 10.1097/MOL.0b013e32832dd4c7. Review. PubMed PMID: 19550325. 2: Farooqui AA, Ong WY, Horrocks LA. Inhibitors of brain phospholipase A2 activity: their neuropharmacological effects and therapeutic importance for the treatment of neurologic disorders. Pharmacol Rev. 2006 Sep;58(3):591-620. Review. PubMed PMID: 16968951. 3: Meyer MC, Rastogi P, Beckett CS, McHowat J. Phospholipase A2 inhibitors as potential anti-inflammatory agents. Curr Pharm Des. 2005;11(10):1301-12. Review. PubMed PMID: 15853686.