MedKoo Cat#: 563279 | Name: AZA197

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AZA197 is a selective Cdc42 inhibitor. It acts by suppressing primary colon cancer growth and prolonging survival in a preclinical mouse xenograft model by downregulation of PAK1 activity.

Chemical Structure

AZA197
AZA197
CAS#1249398-09-1

Theoretical Analysis

MedKoo Cat#: 563279

Name: AZA197

CAS#: 1249398-09-1

Chemical Formula: C24H36N6

Exact Mass: 408.3001

Molecular Weight: 408.59

Elemental Analysis: C, 70.55; H, 8.88; N, 20.57

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
AZA197; AZA-197; AZA 197;
IUPAC/Chemical Name
N4-(2-(1H-indol-3-yl)ethyl)-N2-(5-(diethylamino)pentan-2-yl)-6-methylpyrimidine-2,4-diamine
InChi Key
SUXUDORZKKZLJK-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H36N6/c1-5-30(6-2)15-9-10-18(3)27-24-28-19(4)16-23(29-24)25-14-13-20-17-26-22-12-8-7-11-21(20)22/h7-8,11-12,16-18,26H,5-6,9-10,13-15H2,1-4H3,(H2,25,27,28,29)
SMILES Code
CC1=NC(NC(C)CCCN(CC)CC)=NC(NCCC2=CNC3=C2C=CC=C3)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 408.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Goodman RB, Forstrom JW, Osborn SG, Chi EY, Martin TR. Identification of two neutrophil chemotactic peptides produced by porcine alveolar macrophages. J Biol Chem. 1991 May 5;266(13):8455-63. PubMed PMID: 1850745.