MedKoo Cat#: 124792 | Name: RIG012
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

RIG012 is a potent RIG-I inhibitor. It inhibits IFN-β and ISG hRsad2 expression.

Chemical Structure

RIG012
RIG012
CAS# 2642218-43-5

Theoretical Analysis

MedKoo Cat#: 124792

Name: RIG012

CAS#: 2642218-43-5

Chemical Formula: C23H21NO3

Exact Mass: 359.1521

Molecular Weight: 359.43

Elemental Analysis: C, 76.86; H, 5.89; N, 3.90; O, 13.35

Price and Availability

Size Price Availability Quantity
100mg USD 950.00 2 Weeks
200mg USD 1,650.00 2 Weeks
500mg USD 2,650.00 2 Weeks
1g USD 3,950.00 2 Weeks
2g USD 6,850.00 2 Weeks
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Related CAS #
No Data
Synonym
RIG012; RIG-012; RIG 012
IUPAC/Chemical Name
4-(benzyloxy)-3,3-diethyl-2H-benzo[g]indole-2,5(3H)-dione
InChi Key
OEWZCENSPLZNPQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H21NO3/c1-3-23(4-2)18-19(24-22(23)26)16-12-8-9-13-17(16)20(25)21(18)27-14-15-10-6-5-7-11-15/h5-13H,3-4,14H2,1-2H3
SMILES Code
O=C1N=C2C3=C(C=CC=C3)C(C(OCC4=CC=CC=C4)=C2C1(CC)CC)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 359.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Rawling DC, Jagdmann GE Jr, Potapova O, Pyle AM. Small-Molecule Antagonists of the RIG-I Innate Immune Receptor. ACS Chem Biol. 2020 Feb 21;15(2):311-317. doi: 10.1021/acschembio.9b00810. Epub 2020 Jan 27. PMID: 31944652.