MedKoo Cat#: 413699 | Name: Diclofenac deanol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Diclofenac deanol is a nonsteroidal anti-inflammatory drug (NSAID) of the phenylacetic acid class with anti-inflammatory, analgesic, and antipyretic properties. Contrary to the action of many traditional NSAIDs, diclofenac inhibits cyclooxygenase (COX)-2 enzyme with greater potency than it does COX-1.

Chemical Structure

Diclofenac deanol
Diclofenac deanol
CAS#81811-14-5 (deanol)

Theoretical Analysis

MedKoo Cat#: 413699

Name: Diclofenac deanol

CAS#: 81811-14-5 (deanol)

Chemical Formula: C18H22Cl2N2O3

Exact Mass: 384.1007

Molecular Weight: 385.29

Elemental Analysis: C, 56.11; H, 5.76; Cl, 18.40; N, 7.27; O, 12.46

Price and Availability

This product was removed for the commercial reasons.
Synonym
Diclofenac deanol
IUPAC/Chemical Name
Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, compd. with 2-(dimethylamino)ethanol (1:1)
InChi Key
AINBLHPPOHIAEC-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H11Cl2NO2.C4H11NO/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19;1-5(2)3-4-6/h1-7,17H,8H2,(H,18,19);6H,3-4H2,1-2H3
SMILES Code
O=C(O)CC1=CC=CC=C1NC2=C(Cl)C=CC=C2Cl.CN(CCO)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 385.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: O'Connor KM, Corrigan OI. Preparation and characterisation of a range of diclofenac salts. Int J Pharm. 2001 Sep 11;226(1-2):163-79. doi: 10.1016/s0378-5173(01)00800-6. PMID: 11532579. 2: O'Connor KM, Corrigan OI. Effect of a basic organic excipient on the dissolution of diclofenac salts. J Pharm Sci. 2002 Oct;91(10):2271-81. doi: 10.1002/jps.10222. PMID: 12226854.