MedKoo Cat#: 413652 | Name: Succinylcholine Free Base

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Succinylcholine Free Base is a quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.

Chemical Structure

Succinylcholine Free Base
Succinylcholine Free Base
CAS#306-40-1 (free base)

Theoretical Analysis

MedKoo Cat#: 413652

Name: Succinylcholine Free Base

CAS#: 306-40-1 (free base)

Chemical Formula: C14H30N2O42+

Exact Mass: 290.2195

Molecular Weight: 290.40

Elemental Analysis: C, 57.90; H, 10.41; N, 9.65; O, 22.04

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Succinylcholine Free Base; HSDB3254; HSDB-3254; HSDB 3254
IUPAC/Chemical Name
Ethanaminium, 2,2'-((1,4-dioxo-1,4-butanediyl)bis(oxy))bis(N,N,N-trimethyl-
InChi Key
AXOIZCJOOAYSMI-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H30N2O4/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6/h7-12H2,1-6H3/q+2
SMILES Code
O=C(OCC[N+](C)(C)C)CCC(OCC[N+](C)(C)C)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 290.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sparr HJ, Jöhr M. Succinylcholin-Update [Succinylcholine--update]. Anaesthesist. 2002 Jul;51(7):565-75. German. doi: 10.1007/s00101-002-0324-7. PMID: 12243044. 2: Plaud B. Joyeux anniversaire succinylcholine ! [Happy birthday succinylcholine!]. Ann Fr Anesth Reanim. 2012 Oct;31(10):770-2. French. doi: 10.1016/j.annfar.2012.08.006. Epub 2012 Sep 28. PMID: 23021935. 3: Miller R. Will succinylcholine ever disappear? Anesth Analg. 2004 Jun;98(6):1674-5. doi: 10.1213/01.ane.0000126935.87196.4c. PMID: 15155326. 4: Suparschi V, Sigaut S, Paugam-Burtz C. Prolonged muscle relaxation following succinylcholine administration in a cirrhotic patient: A case report. Eur J Anaesthesiol. 2019 Nov;36(11):883-884. doi: 10.1097/EJA.0000000000001057. PMID: 31580290. 5: Gronert GA, Dotin LN, Ritchey CR, Mason AD Jr. Succinylcholine-induced hyperkalemia in burned patients. II. Anesth Analg. 1969 Nov-Dec;48(6):958-62. PMID: 5391392. 6: Geyer BC, Larrimore KE, Kilbourne J, Kannan L, Mor TS. Reversal of succinylcholine induced apnea with an organophosphate scavenging recombinant butyrylcholinesterase. PLoS One. 2013;8(3):e59159. doi: 10.1371/journal.pone.0059159. Epub 2013 Mar 11. PMID: 23536865; PMCID: PMC3594170. 7: Smith RB. Hyperkalaemia following succinylcholine administration in neurological disorders: a review. Can Anaesth Soc J. 1971 Mar;18(2):199-201. doi: 10.1007/BF03025450. PMID: 4929450. 8: OCHS S, ANNIS B, MUKHERJEE AK. Succinylcholine and muscle excitability. Science. 1960 Jun 3;131(3414):1679-80. doi: 10.1126/science.131.3414.1679. PMID: 14428224. 9: Warner DO. Intramuscular succinylcholine and laryngospasm. Anesthesiology. 2001 Oct;95(4):1039-40. doi: 10.1097/00000542-200110000-00044. PMID: 11605908. 10: Dexter F, Gan TJ, Naguib M, Lubarsky DA. Cost identification analysis for succinylcholine. Anesth Analg. 2001 Mar;92(3):693-9. doi: 10.1097/00000539-200103000-00028. PMID: 11226104.