7-Hydroxychlorpromazine | CAS#2095-62-7 | Metabolite

MedKoo Cat#: 150072 | Name: 7-Hydroxychlorpromazine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

7-Hydroxychlorpromazine is a member of phenothiazines. 7-hydroxy Chlorpromazine is an active metabolite of chlorpromazine.

Chemical Structure

7-Hydroxychlorpromazine

CAS#2095-62-7

Theoretical Analysis

MedKoo Cat#: 150072

Name: 7-Hydroxychlorpromazine

CAS#: 2095-62-7

Chemical Formula: C17H19ClN2OS

Exact Mass: 334.0907

Molecular Weight: 334.86

Elemental Analysis: C, 60.98; H, 5.72; Cl, 10.59; N, 8.37; O, 4.78; S, 9.57

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

7-Hydroxychlorpromazine; 7-OCPZ;

IUPAC/Chemical Name

8-chloro-10-[3-(dimethylamino)propyl]phenothiazin-3-ol

InChi Key

HICFFJZGXWEIHN-UHFFFAOYSA-N

InChi Code

1S/C17H19ClN2OS/c1-19(2)8-3-9-20-14-6-5-13(21)11-17(14)22-16-7-4-12(18)10-15(16)20/h4-7,10-11,21H,3,8-9H2,1-2H3

SMILES Code

OC1=CC=C2N(CCCN(C)C)C3=C(C=CC(Cl)=C3)SC2=C1

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 334.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Dingell JV, Sossi N. Studies on the glucuronidation of 7-hydroxychlorpromazine in vitro. Drug Metab Dispos. 1977 Jul-Aug;5(4):397-404. PMID: 19219. 2: PERRY TL, CULLING CF, BERRY K, HANSEN S. 7-HYDROXYCHLORPROMAZINE: POTENTIAL TOXIC DRUG METABOLITE IN PSYCHIATRIC PATIENTS. Science. 1964 Oct 2;146(3640):81-3. doi: 10.1126/science.146.3640.81. PMID: 14173037. 3: Yeung PK, McKay G, Ramshaw IA, Hubbard JW, Midha KK. A comparison of two radioimmunoassays for 7-hydroxychlorpromazine: rabbit polyclonal antibodies vs. mouse monoclonal antibodies. J Pharmacol Exp Ther. 1985 Jun;233(3):816-22. PMID: 4009490. 4: Bunney BS, Aghajanian GK. A comparison of the effects of chlorpromazine, 7-hydroxychlorpromazine and chlorpromazine sulfoxide on the activity of central dopaminergic neurons. Life Sci. 1974 Jul 15;15(2):309-18. doi: 10.1016/0024-3205(74)90221-5. PMID: 4549921.