Zorubicin HCl is an anthracycline antineoplastic agent that targets topoisomerase II, disrupting DNA replication and transcription by stabilizing the cleavage complex and inducing double-strand breaks. It also generates reactive oxygen species (ROS), causing oxidative DNA damage and triggering apoptosis. This compound has been explored for treating solid tumors and hematologic malignancies, though its clinical use remains limited compared to other anthracyclines.
MedKoo Cat#: 413482
Name: Zorubicin HCl
CAS#: 36508-71-1 (HCl)
Chemical Formula: C34H36ClN3O10
Exact Mass: 0.0000
Molecular Weight: 682.12
Elemental Analysis: C, 59.87; H, 5.32; Cl, 5.20; N, 6.16; O, 23.45
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| To be determined | 0.0 | 100.00 |
The following data is based on the product molecular weight 682.12 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
