ZINC77292789 | CAS#116783-35-8

MedKoo Cat#: 555925 | Name: ZINC77292789

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ZINC77292789 is a reagent for making synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn Antigen Isomer Induces the Production of Antibodies against Tumor Cells. ZINC77292789 was a starting material to make trimeric MUC1 immunodominant motif antigen-based anti-cancer vaccine candidates.

Chemical Structure

ZINC77292789

CAS#116783-35-8

Theoretical Analysis

MedKoo Cat#: 555925

Name: ZINC77292789

CAS#: 116783-35-8

Chemical Formula: C33H38N2O13

Exact Mass: 670.2374

Molecular Weight: 670.67

Elemental Analysis: C, 59.10; H, 5.71; N, 4.18; O, 31.01

Price and Availability

Size	Price	Availability
100mg	USD 1,950.00	2 Weeks
200mg	USD 2,950.00	2 Weeks
500mg	USD 3,950.00	2 Weeks
1g	USD 4,950.00	2 Weeks
2g	USD 8,450.00	2 Weeks

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Related CAS #

No Data

Synonym

Fmoc-Thr[GalNAc(Ac)3-alpha-D]-OH; ZINC77292789; ZINC-77292789; ZINC 77292789;

IUPAC/Chemical Name

N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-((2S,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)-L-threonine

InChi Key

OXLCJWGAUPPZQJ-ZNHCDWFHSA-N

InChi Code

InChI=1S/C33H38N2O13/c1-16(27(31(40)41)35-33(42)44-14-25-23-12-8-6-10-21(23)22-11-7-9-13-24(22)25)45-32-28(34-17(2)36)30(47-20(5)39)29(46-19(4)38)26(48-32)15-43-18(3)37/h6-13,16,25-30,32H,14-15H2,1-5H3,(H,34,36)(H,35,42)(H,40,41)/t16-,26-,27+,28-,29+,30-,32+/m1/s1

SMILES Code

C[C@@H](O[C@@H]1[C@H](NC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H](COC(C)=O)O1)[C@H](NC(OCC2C3=CC=CC=C3C4=CC=CC=C24)=O)C(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Therapeutic vaccines have been regarded as a very promising treatment modality against cancer. Tumor-assocd. MUC1 is a promising antigen for the design of antitumor vaccines.

Instruction

View handling instruction

	Solvent	mg/mL	mM
Solubility
	To be determined	0.0	0.00

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 670.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Ju T, Aryal RP, Kudelka MR, Wang Y, Cummings RD. The Cosmc connection to the Tn antigen in cancer. Cancer Biomark. 2014 Jan 1;14(1):63-81. doi: 10.3233/CBM-130375. PMID: 24643043; PMCID: PMC5808877.