MedKoo Cat#: 558811 | Name: FAM alkyne, 5-isomer
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

FAM (fluorescein) alkyne for copper-catalyzed Click chemistry, high purity (97+%) 5-isomer

Chemical Structure

FAM alkyne, 5-isomer
FAM alkyne, 5-isomer
CAS#510758-19-7

Theoretical Analysis

MedKoo Cat#: 558811

Name: FAM alkyne, 5-isomer

CAS#: 510758-19-7

Chemical Formula: C24H15NO6

Exact Mass: 413.0899

Molecular Weight: 413.39

Elemental Analysis: C, 69.73; H, 3.66; N, 3.39; O, 23.22

Price and Availability

Size Price Availability Quantity
10mg USD 350.00 2 Weeks
25mg USD 650.00 2 Weeks
50mg USD 950.00 2 Weeks
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Synonym
FAM alkyne, 5-isomer , FAM alkyne 5-isomer, FAM alkyne-5-isomer; 5-FAM-Alkyne; 5-FAM alkyne;
IUPAC/Chemical Name
3',6'-dihydroxy-3-oxo-N-(prop-2-yn-1-yl)-3H-spiro[isobenzofuran-1,9'-xanthene]-5-carboxamide
InChi Key
UNBAJBIGCBVWJU-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H15NO6/c1-2-9-25-22(28)13-3-6-17-16(10-13)23(29)31-24(17)18-7-4-14(26)11-20(18)30-21-12-15(27)5-8-19(21)24/h1,3-8,10-12,26-27H,9H2,(H,25,28)
SMILES Code
OC1=CC=C(C2(C3=CC=C(C(NCC#C)=O)C=C3C(O2)=O)C(C=CC(O)=C4)=C4O5)C5=C1
Appearance
Solid powder
Purity
>97% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 413.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1.Synakewicz, M.; Bauer, D.; Rief, M.; Itzhaki, L.S. Bioorthogonal protein-DNA conjugation methods for force spectroscopy. Scientific Reports, 2019, 9, 13820. doi: 10.1038/s41598-019-49843-1 2. van der Meer, S.B.; Loza, K.; Wey, K.; Heggen, M.; Beuck, C.; Bayer, P.; Epple, M. Click Chemistry on the Surface of Ultrasmall Gold Nanoparticles (2 nm) for Covalent Ligand Attachment Followed by NMR Spectroscopy , 2019, 35(22), 7191–7204. doi: 10.1021/acs.langmuir.9b00295 3. Rojas-Sánchez, L.; Sokolova, V.; Riebe, S.; Voskuhl, J.; Epple, M. Covalent Surface Functionalization of Calcium Phosphate Nanoparticles with Fluorescent Dyes by Copper-Catalysed and by Strain-Promoted Azide-Alkyne Click Chemistry. ChemNanoMat, 2019, 5(4), 436–446. doi: 10.1002/cnma.201800509 4. Liang, S.; Guan, Y.; Zhang, Y. Layer-by-Layer Assembly of Microgel Colloidal Crystals via Photoinitiated Alkyne–Azide Click Reaction. ACS Omega, 2019, 4(3), 5650–5660. doi: 10.1021/acsomega.9b00354 5. Ganapathy, U.S.; Bai, L.; Wei, L.; Eckartt, K.A.; Lett, C.M.; Previti, M.L.; Carrico, I.S.; Seeliger, J.C. Compartment-Specific Labeling of Bacterial Periplasmic Proteins by Peroxidase-Mediated Biotinylation. ACS Infectious Diseases, 2018, 4(6), 918–925. doi: 10.1021/acsinfecdis.8b00044 6. Stadler, D.; Siribbal, S.M.; Gessner, I.; Öz, S.; Ilyas, S.; Mathur, S. Asymmetric attachment and functionalization of plasmonic nanoparticles on ceramic interfaces. Journal of Nanostructure in Chemistry, 2018, 8(1), 33–44. doi: 10.1007/s40097-018-0252-y 7. Shi, P.; Ju, E.; Yan, Z.; Gao, N.; Wang, J.; Hou, J.; Zhang, Y.; Ren, J.; Qu, X. Spatiotemporal control of cell-cell reversible interactions using molecular engineering. Nature communications, 2016, 7, 13088. doi: 10.1038/ncomms13088 8. Lu, X.; Jia, F.; Tan, X.; Wang, D.; Cao, X.; Zheng, J.; Zhang, K. Effective Antisense Gene Regulation via Noncationic, Polyethylene Glycol Brushes. Journal of the American Chemical Society, 2016, 138(29), 9097–9100. doi: 10.1021/jacs.6b05787 9. Ilnitskaya, E.V.; Kononevich, Y.N.; Muzafarov, A.M.; Rzhevskiy, S.A.; Shadrin, I.A.; Babaev, E.V.; Martynov, V.I.; Pakhomov, A.A. Preparation and application of a BODIPY-labeled probe for a real-time polymerase chain reaction. Russian Journal of Bioorganic Chemistry, 2015, 41(4), 451–453. doi: 10.1134/S1068162015040068