N-(4,6-divinyl-1,3,5-triazin-2-yl)-PEG8-NHS ester is a novel cysteine binder coupled to a terminal NHS ester bound by a PEG linker. The divinyltriazine rapidly binds two cysteine residues to form macrocyclic peptides under mild conditions. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
MedKoo Cat#: 122097
Name: N-(4,6-divinyl-1,3,5-triazin-2-yl)-PEG8-NHS ester
CAS#: N/A
Chemical Formula: C33H52N6O13
Exact Mass: 740.3592
Molecular Weight: 740.81
Elemental Analysis: C, 53.50; H, 7.08; N, 11.34; O, 28.08
The following data is based on the product molecular weight 740.81 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |