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MedKoo Cat#: 575377 | Name: FE-200041

Description:

WARNING: This product is for research use only, not for human or veterinary use.

FE-200041 is a peripheral efficacious kappa opioid agonist.

Chemical Structure

FE-200041
FE-200041
CAS#212710-26-4

Theoretical Analysis

MedKoo Cat#: 575377

Name: FE-200041

CAS#: 212710-26-4

Chemical Formula: C30H44N8O4

Exact Mass: 580.3486

Molecular Weight: 580.73

Elemental Analysis: C, 62.05; H, 7.64; N, 19.30; O, 11.02

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
D-Phe-D-phe-D-nle-D-arg-NH2; FE-200041; FE200041; FE 200041
IUPAC/Chemical Name
D-Argininamide, D-phenylalanyl-D-phenylalanyl-D-norleucyl-
InChi Key
RUOXNQGHBFJAES-ZGFBMJKBSA-N
InChi Code
InChI=1S/C30H44N8O4/c1-2-3-15-24(28(41)36-23(26(32)39)16-10-17-35-30(33)34)37-29(42)25(19-21-13-8-5-9-14-21)38-27(40)22(31)18-20-11-6-4-7-12-20/h4-9,11-14,22-25H,2-3,10,15-19,31H2,1H3,(H2,32,39)(H,36,41)(H,37,42)(H,38,40)(H4,33,34,35)/t22-,23-,24-,25-/m1/s1
SMILES Code
CCCC[C@@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@H](CCCNC(=N)N)C(=O)N
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 580.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Vanderah TW, Schteingart CD, Trojnar J, Junien JL, Lai J, Riviere PJ. FE200041 (D-Phe-D-Phe-D-Nle-D-Arg-NH2): A peripheral efficacious kappa opioid agonist with unprecedented selectivity. J Pharmacol Exp Ther. 2004 Jul;310(1):326-33. doi: 10.1124/jpet.104.065391. Epub 2004 Mar 1. PMID: 14993260. 2. Negus SS, O'Connell R, Morrissey E, Cheng K, Rice KC. Effects of peripherally restricted κ opioid receptor agonists on pain-related stimulation and depression of behavior in rats. J Pharmacol Exp Ther. 2012 Mar;340(3):501-9. doi: 10.1124/jpet.111.186783. Epub 2011 Nov 29. PMID: 22128346; PMCID: PMC3286312.