Olgotrelvir, also known as STI-1558, is an antiviral. Olgotrelvir is a prodrug that first converts to its active form, AC1115. AC1115 is believed to work by inhibiting the SARS-CoV-2 main protease (also known as 3C-like protease). This protein is a crucial enzyme responsible for cleaving viral polyproteins into functional subunits essential for viral replication. By binding to the active site of the protease, the drug prevents this cleavage process, effectively halting viral assembly and impeding the virus's ability to produce future virions.
MedKoo Cat#: 140266
Name: Olgotrelvir
CAS#: 2763596-71-8
Chemical Formula: C22H30N4O7S
Exact Mass: 494.1835
Molecular Weight: 494.56
Elemental Analysis: C, 53.43; H, 6.11; N, 11.33; O, 22.64; S, 6.48
The following data is based on the product molecular weight 494.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
