MedKoo Cat#: 581735 | Name: Decamethonium iodide
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Decamethonium is a depolarizing muscle relaxant or neuromuscular blocking agent,[1] and is used in anesthesia to induce paralysis.

Chemical Structure

Decamethonium iodide
Decamethonium iodide
CAS#1420-40-2 (iodide)

Theoretical Analysis

MedKoo Cat#: 581735

Name: Decamethonium iodide

CAS#: 1420-40-2 (iodide)

Chemical Formula: C16H38I2N2

Exact Mass: 512.1124

Molecular Weight: 512.30

Elemental Analysis: C, 37.51; H, 7.48; I, 49.54; N, 5.47

Price and Availability

Size Price Availability Quantity
5g USD 350.00 2 Weeks
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Synonym
Decamethonium iodide; Decamethonium diiodide; Decamethonium iodatum; Dekamethoniumjodid.
IUPAC/Chemical Name
1,10-Decanediaminium, N,N,N,N(sup 1),N(sup 1),N(sup 1)-hexamethyl-, diiodide (9CI)
InChi Key
BDJLHVDTSQRLRP-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H38N2.2HI/c1-17(2,3)15-13-11-9-7-8-10-12-14-16-18(4,5)6;;/h7-16H2,1-6H3;2*1H/q+2;2*-1
SMILES Code
[N+](CCCCCCCCCC[N+](C)(C)C)(C)(C)C.[IH-].[IH-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 512.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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PubMed PMID: 26990888; PubMed Central PMCID: PMC4941771. 4: Nazarchuk OA. [АNTISEPTICS: MODERN STRATEGY OF STRUGGLE WITH CAUSING AGENTS OF THE ІNFECTION COMPLICATIONS]. Klin Khir. 2016;(9):59-61. Ukrainian. PubMed PMID: 30265488. 5: Bajda M, Panek D, Hebda M, Więckowska A, Guzior N, Malawska B. SEARCH FOR POTENTIAL CHOLINESTERASE INHIBITORS FROM THE ZINC DATABASE BY VIRTUAL SCREENING METHOD. Acta Pol Pharm. 2015 Jul-Aug;72(4):737-45. PubMed PMID: 26647631. 6: Li DC, Nichols CG, Sala-Rabanal M. Role of a Hydrophobic Pocket in Polyamine Interactions with the Polyspecific Organic Cation Transporter OCT3. J Biol Chem. 2015 Nov 13;290(46):27633-43. doi: 10.1074/jbc.M115.668913. Epub 2015 Sep 24. PubMed PMID: 26405039; PubMed Central PMCID: PMC4646014. 7: Arseniuk VV, Bartosh AM, Vasul'ianov DS, Voĭtenko II, Hryniv OV, Smotrov MI. [Probability of incidence of abdominal adhesional process in peritonitis, depending on the sanation preparation applied]. Klin Khir. 2014 Dec;(12):78. Ukrainian. PubMed PMID: 25842895. 8: Su G, Greaves AK, Gauthier L, Letcher RJ. Liquid chromatography-electrospray-tandem mass spectrometry method for determination of organophosphate diesters in biotic samples including Great Lakes herring gull plasma. J Chromatogr A. 2014 Dec 29;1374:85-92. doi: 10.1016/j.chroma.2014.11.022. Epub 2014 Nov 26. PubMed PMID: 25476687. 9: Kiss T, Krajcs N, Pirger Z, Hernádi L. Nicotinic acetylcholine receptors containing the α7-like subunit mediate contractions of muscles responsible for space positioning of the snail, Helix pomatia L. tentacle. PLoS One. 2014 Oct 10;9(10):e109538. doi: 10.1371/journal.pone.0109538. eCollection 2014. PubMed PMID: 25303328; PubMed Central PMCID: PMC4193815. 10: Paliĭ GK, Nazarchuk AA, Kulakov AI, Nazarchuk GG, Paliĭ DV, Bereza BN, Oleĭnik DP. [Kinetics of decamethoxine, an antimicrobial agent]. Antibiot Khimioter. 2014;59(3-4):7-9. Russian. PubMed PMID: 25300114. 11: Nazirov FN, Aripova NU, Makhkamova MN, Dzhamalov SI, Pulatov MM, Magzumov IKh, Isroilov BN. [Use of antiseptic dekasan in complex treatment of peritonitis]. Klin Khir. 2014 Jan;(1):26-7. Russian. PubMed PMID: 24923145. 12: Aripova NU, Magzumov IKh. [Sanation of biliary system using antiseptic decasan in complex treatment of cholangitis]. Klin Khir. 2014 Feb;(2):20-2. Russian. PubMed PMID: 24923115. 13: Nowlan NC, Chandaria V, Sharpe J. Immobilized chicks as a model system for early-onset developmental dysplasia of the hip. J Orthop Res. 2014 Jun;32(6):777-85. doi: 10.1002/jor.22606. Epub 2014 Mar 3. PubMed PMID: 24590854. 14: Nazarchuk OA, Vernyhorods'kyĭ SV, Paliĭ VH, Nazarchuk HH, Paliĭ DV, Honchar OO, Zadereĭ NV. [Local impact of antiseptic medical textile on tissues of organism]. Klin Khir. 2013 Jul;(7):61-4. Ukrainian. PubMed PMID: 24283049. 15: Widdifield CM, Cavallo G, Facey GA, Pilati T, Lin J, Metrangolo P, Resnati G, Bryce DL. Multinuclear Solid-State Magnetic Resonance as a Sensitive Probe of Structural Changes upon the Occurrence of Halogen Bonding in Co-crystals. Chemistry. 2013 Sep 2;19(36):11949-62. doi: 10.1002/chem.201300809. Epub 2013 Jul 26. PubMed PMID: 23893705. 16: Argirova MD, Stefanova ID, Krustev AD. New biological properties of coffee melanoidins. Food Funct. 2013 Aug;4(8):1204-8. doi: 10.1039/c3fo60025d. PubMed PMID: 23712216. 17: Boĭko VV, Lohachev VK, Tymchenko MIe. [Application of decamethoxin solution in the treatment of surgical peritonitis]. Klin Khir. 2012 Dec;(12):16-9. Ukrainian. PubMed PMID: 23610813. 18: Brown TC. Aspects of depolarizing neuromuscular blockers: decamethonium and suxamethonium. Paediatr Anaesth. 2013 Sep;23(9):868-70. doi: 10.1111/pan.12122. Epub 2013 Feb 11. PubMed PMID: 23398375. 19: Paliĭ GK, Nazarchuk AA, Paliĭ DV, Nazarchuk GG, Gonchar OO, Sukhliak VV, Trofimenko IuIu, Zadereĭ NV, Stukan OK. [Antimicrobial properties of antiseptic composite with prolonged action]. Antibiot Khimioter. 2013;58(3-4):14-8. Russian. PubMed PMID: 24640146. 20: Barbacci D, Jackson SN, Muller L, Egan T, Lewis EK, Schultz JA, Woods AS. Cellular membrane phospholipids act as a depository for quaternary amine containing drugs thus competing with the acetylcholine/nicotinic receptor. J Proteome Res. 2012 Jun 1;11(6):3382-9. doi: 10.1021/pr300184g. Epub 2012 Apr 30. PubMed PMID: 22506649; PubMed Central PMCID: PMC4144022.