ArgTX-93 TFA | CAS#1161025-20-2 | NMDAR antagonist| MedKoo

MedKoo Cat#: 555309 | Name: ArgTX-93 TFA

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ArgTX-93 is a highly potent and subfamily selective antagonist of the NMDARs and AMPARs.

Chemical Structure

ArgTX-93 TFA

CAS#1161025-20-2 (TFA)

Theoretical Analysis

MedKoo Cat#: 555309

Name: ArgTX-93 TFA

CAS#: 1161025-20-2 (TFA)

Chemical Formula: C36H56F9N9O12

Exact Mass:

Molecular Weight: 977.88

Elemental Analysis: C, 44.22; H, 5.77; F, 17.49; N, 12.89; O, 19.63

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

1209469-05-5 (free base) 1161025-20-2 (TFA)

Synonym

ArgTX-93; ArgTX 93; ArgTX93; ArgTX-93 TFA salt.

IUPAC/Chemical Name

(S)-N1-(9-((3-((S)-2-amino-5-guanidinopentanamido)propyl)amino)nonyl)-2-(2-(2,4-dihydroxyphenyl)acetamido)succinamide tris(2,2,2-trifluoroacetate)

InChi Key

BCFCAKJJQFWJAI-HFYJLKHYSA-N

InChi Code

InChI=1S/C30H53N9O6.3C2HF3O2/c31-23(10-8-16-38-30(33)34)28(44)36-17-9-14-35-13-6-4-2-1-3-5-7-15-37-29(45)24(20-26(32)42)39-27(43)18-21-11-12-22(40)19-25(21)41;3*3-2(4,5)1(6)7/h11-12,19,23-24,35,40-41H,1-10,13-18,20,31H2,(H2,32,42)(H,36,44)(H,37,45)(H,39,43)(H4,33,34,38);3*(H,6,7)/t23-,24-;;;/m0.../s1

SMILES Code

O=C(NCCCCCCCCCNCCCNC([C@@H](N)CCCNC(N)=N)=O)[C@@H](NC(CC1=CC=C(O)C=C1O)=O)CC(N)=O.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 977.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Nørager NG, Poulsen MH, Jensen AG, Jeppesen NS, Kristensen AS, Strømgaard K. Structure-activity relationship studies of N-methylated and N-hydroxylated spider polyamine toxins as inhibitors of ionotropic glutamate receptors. J Med Chem. 2014 Jun 12;57(11):4940-9. doi: 10.1021/jm5004705. Epub 2014 May 29. PubMed PMID: 24824658.