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MedKoo Cat#: 597749 | Name: ARL 15849XX

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ARL 15849XX is a CCK-8 analog and a novel anti-obesity agent.

Chemical Structure

ARL 15849XX
CAS#152548-39-5

Theoretical Analysis

MedKoo Cat#: 597749

Name: ARL 15849XX

CAS#: 152548-39-5

Chemical Formula: C47H60N8O13S

Exact Mass: 976.4001

Molecular Weight: 977.10

Elemental Analysis: C, 57.77; H, 6.19; N, 11.47; O, 21.29; S, 3.28

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
ARL 15849XX; ARL-15849XX; ARL15849XX; FPL 15849; FPL-15849; FPL15849; AR-R-15849; AR-R15849; AR-R 15849;
IUPAC/Chemical Name
(4S,10S,13S,16S)-10-((1H-indol-3-yl)methyl)-16-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)carbamoyl)-4,13-dibutyl-15-methyl-2,5,8,11,14-pentaoxo-1-(4-(sulfooxy)phenyl)-3,6,9,12,15-pentaazaoctadecan-18-oic acid
InChi Key
UPYRHIUUCMHYRX-MQDBWYGVSA-N
InChi Code
InChI=1S/C47H60N8O13S/c1-4-6-16-35(51-40(56)24-30-19-21-32(22-20-30)68-69(65,66)67)44(61)50-28-41(57)52-38(25-31-27-49-34-18-12-11-15-33(31)34)45(62)53-36(17-7-5-2)47(64)55(3)39(26-42(58)59)46(63)54-37(43(48)60)23-29-13-9-8-10-14-29/h8-15,18-22,27,35-39,49H,4-7,16-17,23-26,28H2,1-3H3,(H2,48,60)(H,50,61)(H,51,56)(H,52,57)(H,53,62)(H,54,63)(H,58,59)(H,65,66,67)/t35-,36-,37-,38-,39-/m0/s1
SMILES Code
O=C(N)[C@H](CC1=CC=CC=C1)NC([C@H](CC(O)=O)N(C([C@H](CCCC)NC([C@H](CC2=CNC3=C2C=CC=C3)NC(CNC([C@H](CCCC)NC(CC4=CC=C(OS(=O)(O)=O)C=C4)=O)=O)=O)=O)=O)C)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 977.10 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Willson VJ, Preston JR, Lockley WJ, Singh J, Wilkinson D. A radioimmunoassay combined with solid-phase extraction for the determination of a novel anti-obesity agent, ARL 15849XX, in dog plasma. J Pharm Biomed Anal. 1996 Mar;14(5):593-600. PubMed PMID: 8738189. 2: Simmons RD, Kaiser FC, Hudzik TJ. Behavioral effects of AR-R 15849, a highly selective CCK-A agonist. Pharmacol Biochem Behav. 1999 Mar;62(3):549-57. PubMed PMID: 10080250.