MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 591501 | Name: Duoperone fumarate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Duoperone is a neuroleptic agent. Duoperone blocked d-amphetamine lethality in mice under aggregated conditions when the pretreatment interval was between one hour and seven days.

Chemical Structure

Duoperone fumarate
Duoperone fumarate
CAS#62030-89-1 (fumarate)

Theoretical Analysis

MedKoo Cat#: 591501

Name: Duoperone fumarate

CAS#: 62030-89-1 (fumarate)

Chemical Formula: C32H30F4N2O5S

Exact Mass: 630.1812

Molecular Weight: 630.65

Elemental Analysis: C, 60.94; H, 4.80; F, 12.05; N, 4.44; O, 12.68; S, 5.08

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
62030-88-0 (free base) 62030-89-1 (fumarate)
Synonym
Duoperone fumarate; AHR 6646; AHR-6646; AHR6646
IUPAC/Chemical Name
p-Fluorophenyl 1-(3-(2-(trifluoromethyl)phenothiazin-10-yl)propyl)-4-piperidyl ketone fumarate (1:1)
InChi Key
YETRXLVOWPGIHR-WLHGVMLRSA-N
InChi Code
InChI=1S/C28H26F4N2OS.C4H4O4/c29-22-9-6-19(7-10-22)27(35)20-12-16-33(17-13-20)14-3-15-34-23-4-1-2-5-25(23)36-26-11-8-21(18-24(26)34)28(30,31)32;5-3(6)1-2-4(7)8/h1-2,4-11,18,20H,3,12-17H2;1-2H,(H,5,6)(H,7,8)/b;2-1+
SMILES Code
O=C(O)/C=C/C(O)=O.O=C(C1=CC=C(F)C=C1)C2CCN(CCCN3C4=C(C=CC=C4)SC5=CC=C(C(F)(F)F)C=C35)CC2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 630.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Osman MA, Bhavnagri VP, Pinchbeck FM, Cheng LK, Wright GJ. Determination of duoperone in plasma by high-performance liquid chromatography. J Chromatogr. 1987 Aug 7;419:452-7. PubMed PMID: 2889745. 2: Johnson DN, Turley BG, Jones MR, Coffin CB, Leonard CA, Funderburk WH. AHR-6646: a new, long-acting neuroleptic. Prog Neuropsychopharmacol. 1979;3(5-6):513-20. PubMed PMID: 45570.