MedKoo Cat#: 146218 | Name: Wyerone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Wyerone is a natural furanoterpenoid compound isolated from the roots of Lotus corniculatus and other legumes, known for its antimicrobial and phytoalexin properties. It plays a defensive role in plants by inhibiting the growth of pathogenic fungi and bacteria. The mechanism of action of wyerone involves disruption of microbial cell membranes and interference with essential enzymatic processes. Applications of wyerone are primarily in agricultural and plant pathology research, where it is studied for its potential use in enhancing crop resistance to pathogens.

Chemical Structure

Wyerone
Wyerone
CAS#20079-30-5

Theoretical Analysis

MedKoo Cat#: 146218

Name: Wyerone

CAS#: 20079-30-5

Chemical Formula: C15H14O4

Exact Mass: 258.0892

Molecular Weight: 258.27

Elemental Analysis: C, 69.76; H, 5.46; O, 24.78

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Wyerone;
IUPAC/Chemical Name
methyl (E)-3-(5-((Z)-hept-4-en-2-ynoyl)furan-2-yl)acrylate
InChi Key
NQZCQIDFBYCBAU-JHGYFVHDSA-N
InChi Code
1S/C15H14O4/c1-3-4-5-6-7-13(16)14-10-8-12(19-14)9-11-15(17)18-2/h4-5,8-11H,3H2,1-2H3/b5-4-,11-9+
SMILES Code
CC\C=C/C#CC(=O)C1=CC=C(O1)\C=C\C(=O)OC
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 258.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Méndez-López LF, Sosa de León D, López-Cabanillas Lomelí M, González-Martínez BE, Vázquez-Rodríguez JA. Phytochemicals From Vicia faba Beans as Ligands of the Aryl Hydrocarbon Receptor to Regulate Autoimmune Diseases. Front Nutr. 2022 Mar 4;9:790440. doi: 10.3389/fnut.2022.790440. PMID: 35308285; PMCID: PMC8931403. 2: Fawcett CH, Spencer DM, Wain RL, Fallis AG, Jones ER, Le Quan M, Page CB, Thaller V, Shubrook DC, Whitham PM. Natural acetylenes. XXVII. An antifungal acetylenic furanoid keto-ester (wyerone) from shoots of the broad bean (Vicia faba L.; Fam. Papillionaceae). J Chem Soc Perkin 1. 1968;19:2455-62. doi: 10.1039/j39680002455. PMID: 5693040. 3: Dou Z, Li Q, Zhang J, Zhang X. Exploring the mechanism of Schisandra rubriflora in the treatment of polycystic ovary syndrome based on network pharmacology and molecular docking. J Ovarian Res. 2025 Jan 28;18(1):16. doi: 10.1186/s13048-025-01600-x. PMID: 39875917; PMCID: PMC11773789.